[HTML][HTML] Candida albicans—The Virulence Factors and Clinical Manifestations of Infection

J Talapko, M Juzbašić, T Matijević, E Pustijanac… - Journal of Fungi, 2021 - mdpi.com
Candida albicans is a common commensal fungus that colonizes the oropharyngeal cavity,
gastrointestinal and vaginal tract, and healthy individuals' skin. In 50% of the population, C …

The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

[HTML][HTML] Modulation of immune responses by particle size and shape

MV Baranov, M Kumar, S Sacanna… - Frontiers in …, 2021 - frontiersin.org
The immune system has to cope with a wide range of irregularly shaped pathogens that can
actively move (eg, by flagella) and also dynamically remodel their shape (eg, transition from …

Mechanism of Candida pathogenesis: revisiting the vital drivers

IE Mba, EI Nweze - European Journal of Clinical Microbiology & Infectious …, 2020 - Springer
Candida is the most implicated fungal pathogen in the clinical setting. Several factors play
important roles in the pathogenesis of Candida spp. Multiple transcriptional circuits …

Candidalysin delivery to the invasion pocket is critical for host epithelial damage induced by Candida albicans

S Mogavero, FM Sauer, S Brunke, S Allert… - Cellular …, 2021 - Wiley Online Library
The human pathogenic fungus Candida albicans is a frequent cause of mucosal infections.
Although the ability to transition from the yeast to the hypha morphology is essential for …

[HTML][HTML] Comparative genomics reveals the origin of fungal hyphae and multicellularity

E Kiss, B Hegedüs, M Virágh, T Varga… - Nature …, 2019 - nature.com
Hyphae represent a hallmark structure of multicellular fungi. The evolutionary origins of
hyphae and of the underlying genes are, however, hardly known. By systematically …

[HTML][HTML] “Molding” immunity—modulation of mucosal and systemic immunity by the intestinal mycobiome in health and disease

MW Gutierrez, E van Tilburg Bernardes… - Mucosal …, 2022 - Elsevier
Fungi are important yet understudied contributors to the microbial communities of the
gastrointestinal tract. Starting at birth, the intestinal mycobiome undergoes a period of …

Transcriptional control of hyphal morphogenesis in Candida albicans

S Villa, M Hamideh, A Weinstock, MN Qasim… - FEMS yeast …, 2020 - academic.oup.com
Candida albicans is a multimorphic commensal organism and opportunistic fungal pathogen
in humans. A morphological switch between unicellular budding yeast and multicellular …

Cyclic strain of Poly (methyl methacrylate) surfaces triggered the pathogenicity of Candida albicans

C Montoya, J Kurylec, A Ossa, S Orrego - Acta Biomaterialia, 2023 - Elsevier
Candida albicans is an opportunistic yeast and the primary etiological factor in oral
candidiasis and denture stomatitis. The pathogenesis of C. albicans could be triggered by …

[HTML][HTML] The human gut mycobiome and the specific role of Candida albicans: where do we stand, as clinicians?

S Musumeci, M Coen, A Leidi, J Schrenzel - Clinical Microbiology and …, 2022 - Elsevier
Background The so-called 'mycobiome'has progressively acquired interest and increased
the complexity of our understanding of the human gut microbiota. Several questions are …