Disease manifestations and pathogenic mechanisms of group A Streptococcus
MJ Walker, TC Barnett, JD McArthur… - Clinical microbiology …, 2014 - Am Soc Microbiol
Streptococcus pyogenes, also known as group A Streptococcus (GAS), causes mild human
infections such as pharyngitis and impetigo and serious infections such as necrotizing …
infections such as pharyngitis and impetigo and serious infections such as necrotizing …
Routine use of microbial whole genome sequencing in diagnostic and public health microbiology
Whole genome sequencing (WGS) promises to be transformative for the practice of clinical
microbiology, and the rapidly falling cost and turnaround time mean that this will become a …
microbiology, and the rapidly falling cost and turnaround time mean that this will become a …
Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences
We sequenced the genomes of 3,615 strains of serotype Emm protein 1 (M1) group A
Streptococcus to unravel the nature and timing of molecular events contributing to the …
Streptococcus to unravel the nature and timing of molecular events contributing to the …
A molecular trigger for intercontinental epidemics of group A Streptococcus
The identification of the molecular events responsible for strain emergence, enhanced
virulence, and epidemicity has been a long-pursued goal in infectious diseases research. A …
virulence, and epidemicity has been a long-pursued goal in infectious diseases research. A …
[HTML][HTML] Increasing incidence of invasive group A Streptococcus disease, Idaho, USA, 2008–2019
EM Dunne, S Hutton, E Peterson… - Emerging Infectious …, 2022 - ncbi.nlm.nih.gov
We investigated invasive group A Streptococcus epidemiology in Idaho, USA, during 2008–
2019 using surveillance data, medical record review, and emm (M protein gene) typing …
2019 using surveillance data, medical record review, and emm (M protein gene) typing …
[HTML][HTML] Global genomic epidemiology of Streptococcus pyogenes
Streptococcus pyogenes is one of the Top 10 human infectious disease killers worldwide
causing a range of clinical manifestations in humans. Colonizing a range of ecological …
causing a range of clinical manifestations in humans. Colonizing a range of ecological …
Integrated analysis of population genomics, transcriptomics and virulence provides novel insights into Streptococcus pyogenes pathogenesis
Streptococcus pyogenes causes 700 million human infections annually worldwide, yet,
despite a century of intensive effort, there is no licensed vaccine against this bacterium …
despite a century of intensive effort, there is no licensed vaccine against this bacterium …
Molecular epidemiology and genomics of group A Streptococcus
Streptococcus pyogenes (group A Streptococcus; GAS) is a strict human pathogen with a
very high prevalence worldwide. This review highlights the genetic organization of the …
very high prevalence worldwide. This review highlights the genetic organization of the …
Genome analysis following a national increase in scarlet fever in England 2014
V Chalker, A Jironkin, J Coelho, A Al-Shahib, S Platt… - BMC genomics, 2017 - Springer
Background During a substantial elevation in scarlet fever (SF) notifications in 2014 a
national genomic study was undertaken of Streptococcus pyogenes (Group A Streptococci …
national genomic study was undertaken of Streptococcus pyogenes (Group A Streptococci …
High Incidence of Invasive Group A Streptococcus Disease Caused by Strains of Uncommon emm Types in Thunder Bay, Ontario, Canada
An outbreak of type emm59 invasive group A Streptococcus (iGAS) disease was declared in
2008 in Thunder Bay District, Northwestern Ontario, 2 years after a countrywide emm59 …
2008 in Thunder Bay District, Northwestern Ontario, 2 years after a countrywide emm59 …