Head and neck squamous cell carcinomas (HNSCCs) are caused by tobacco and alcohol
consumption and by infection with high-risk types of human papillomavirus (HPV). Tumours …

Studies of the role of germline or inherited genetic variation on cancer outcome can fall into
three distinct categories. First, the impact of highly penetrant but lowly prevalent mutations of …

MicroRNA (miRNA)-binding site polymorphisms that could contribute to disease risk and
prognosis are rapidly being identified and investigated as this genetic variation may have a …

Laryngeal cancer is known to be associated with smoking and high alcohol consumption.
Nucleotide excision repair (NER) plays a key role in repairing DNA damage induced by …

The study is aimed at establishing the purpose of tumour markers, their application,
classification, diagnostic and therapeutic roles in the management of head and neck cancer …

Cancer hijacks embryonic development and adult wound repair mechanisms to fuel
malignancy. Cancer frequently originates from de-regulated adult stem cells or progenitors …

Epidemiological studies have shown that head and neck cancer (HNC) is a complex
multistage process that in part involves exposure to a combination of carcinogens and the …

Background/purpose Because oral health of patients with head & neck cancer is prone to
disease after radiotherapy, effective and long-lasting oral care program is necessary. We …

Background The genes of base excision repair (BER) pathway have been extensively
studied in the association with various human cancers. We performed a case-control study …

Purpose: From the published literature, we identified 23 germ line sequence variants in 17
genes from hypothesis-generating studies that were associated with prognosis of head and …