In situ self-assembly—the in situ formation of complex materials via biochemical reactions of
monomers—has enhanced the efficacy of drug delivery for cancer therapy and imaging. So …

Transition-metal coordination complexes are emerging as a broad class of supramolecular
crosslinks that can be used to engineer the mechanical properties of advanced structural …

Abstract Poly (glycerol sebacate)(PGS) continues to attract attention for biomedical
applications owing to its favorable combination of properties. Conventionally polymerized by …

During mesenchymal development, the sources of mechanical forces transduced by cells
transition over time from predominantly cell-cell interactions to predominantly cell …

Cell polarization exists in a variety of tissues to regulate cell behaviors and functions. Space
constraint (spatially limiting cell extension) and adhesion induction (guiding adhesome …

Cell behaviors are influenced by the surrounding dynamic microenvironment where the
extracellular matrix (ECM) composed of different micro/nano-structures plays a key role …

The extracellular matrix (ECM) is mechanically inhomogeneous due to the presence of a
wide spectrum of biomacromolecules and hierarchically assembled structures at the …

Biophysical cues of native extracellular matrix (ECM) can affect cellular behavior. Although
static properties of biomaterials have been widely explored, there is a growing interest in …

Microneedle (MN) patches are promising stratagems for transdermal drug delivery owing to
its minimal invasiveness and portability. Particularly, separable MN patches attract more …

The dominant source of thromboembolism in heart comes from the left atrial appendage
(LAA). An occluder can close LAA and significantly reduce the risk of strokes, particularly for …