Mitochondrial dysfunction is implicated in most neurodegenerative diseases, including
Alzheimer's disease (AD). We here combined experimental and computational approaches …

Autofluorescence emission of liver tissue depends on the presence of endogenous
biomolecules able to fluoresce under suitable light excitation. Overall autofluorescence …

A method of rapidly differentiating lung tumor from healthy tissue is extraordinarily needed
for both the diagnosis and the intraoperative margin assessment. We assessed the ability of …

Two-photon fluorescence lifetime imaging microscopy (FLIM) is widely used to capture
autofluorescence signals from cellular components to investigate dynamic physiological …

Optical spectroscopy and imaging approaches offer the potential to noninvasively assess
different aspects of the cellular, extracellular matrix, and scaffold components of engineered …

Advanced stage glioma is the most aggressive form of malignant brain tumors with a short
survival time. Real-time pathology assisted, or image guided surgical procedures that …

Formulation of oxidative phosphorylation and its first observation by means of fluorescence
spectroscopy in the 1960s led to the acceptance of bioenergetics as a new field of studies …

Intravital microscopy (IVM) expands our understanding of cellular and molecular processes,
with applications ranging from fundamental biology to (patho) physiology and immunology …

Automated computational analysis techniques utilizing machine learning have been
demonstrated to be able to extract more data from different imaging modalities compared to …

Direct monitoring of cell death (ie, apoptosis and necrosis) during or shortly after treatment is
desirable in all cancer therapies to determine the outcome. Further differentiation of …