Background Although antipsychotic maintenance treatment is widely recommended to
prevent relapse in chronic psychoses, evidence-based guidelines do not provide clear …

We aimed to identify diagnosis-specific/transdiagnostic/transoutcome multivariable
candidate predictors (MCPs) of key outcomes in mental disorders. We conducted an …

Background Maintenance antipsychotic medication is recommended for people with
schizophrenia or recurrent psychosis, but the adverse effects are burdensome, and …

Microglia are the brain's resident macrophages, which guide various developmental
processes crucial for brain maturation, activity, and plasticity. Microglial progenitors enter the …

With new data about different aspects of schizophrenia being continually generated, it
becomes necessary to periodically revisit exactly what we know. Along with a need to review …

Human cognition is underpinned by structured internal representations that encode
relationships between entities in the world (cognitive maps). Clinical features of …

Background Side-effects of psychiatric medication impair quality of life and functioning.
Furthermore, they contribute to morbidity, mortality, stigma, and poor treatment concordance …

Specific mechanisms underlying gut microbiota alterations in schizophrenia remain
unknown. We aimed to compare gut microbiota between patients with schizophrenia and …

Despite enormous efforts employing various approaches, the molecular pathology in the
schizophrenia brain remains elusive. On the other hand, the knowledge of the association …

Background Schizophrenia is a severe psychiatric disorder with periods of remission and
relapse. As discontinuation of antipsychotic medication is the most important reason for …