Oxidative stress occurs prior to amyloid Aβ plaque formation and tau phosphorylation in Alzheimer's disease: Role of glutathione and metal ions
Alzheimer's disease (AD) is an insidious and progressive neurodegenerative disorder that
affects millions of people worldwide. Although the pathogenesis remains obscure, there are …
affects millions of people worldwide. Although the pathogenesis remains obscure, there are …
Ionic liquids revolutionizing biomedicine: recent advances and emerging opportunities
Y Hu, Y Xing, H Yue, T Chen, Y Diao, W Wei… - Chemical Society …, 2023 - pubs.rsc.org
Ionic liquids (ILs), due to their inherent structural tunability, outstanding miscibility behavior,
and excellent electrochemical properties, have attracted significant research attention in the …
and excellent electrochemical properties, have attracted significant research attention in the …
The neuroprotective effects of targeting key factors of neuronal cell death in neurodegenerative diseases: The role of ER stress, oxidative stress, and …
MS Karvandi, F Sheikhzadeh Hesari… - Frontiers in Cellular …, 2023 - frontiersin.org
Neuronal loss is one of the striking causes of various central nervous system (CNS)
disorders, including major neurodegenerative diseases, such as Alzheimer's disease (AD) …
disorders, including major neurodegenerative diseases, such as Alzheimer's disease (AD) …
Myelin in Alzheimer's disease: culprit or bystander?
M Maitre, H Jeltsch-David, NG Okechukwu… - Acta Neuropathologica …, 2023 - Springer
Alzheimer's disease (AD) is a neurodegenerative disorder with neuronal and synaptic
losses due to the accumulation of toxic amyloid β (Αβ) peptide oligomers, plaques, and …
losses due to the accumulation of toxic amyloid β (Αβ) peptide oligomers, plaques, and …
Angiotensin‐converting enzymes as druggable features of psychiatric and neurodegenerative disorders
TC Santiago, L Parra, JV Nani… - Journal of …, 2023 - Wiley Online Library
The renin‐angiotensin system (RAS) plays essential roles in maintaining peripheral
cardiovascular homeostasis, with its potential roles in the brain only being recognized more …
cardiovascular homeostasis, with its potential roles in the brain only being recognized more …
Neuromodulatory effect of vardenafil on aluminium chloride/d-galactose induced Alzheimer's disease in rats: emphasis on amyloid-beta, p-tau, PI3K/Akt/p53 pathway …
HH Awad, MA Desouky, A Zidan, M Bassem… - …, 2023 - Springer
Dysregulation of protein homeostasis, proteostasis, is a distinctive hallmark of many
neurodegenerative disorders and aging. Deleteriously, the accumulation of aberrant …
neurodegenerative disorders and aging. Deleteriously, the accumulation of aberrant …
The enzymes of the oxidative phase of the pentose phosphate pathway as targets of reactive species: consequences for NADPH production
E Fuentes-Lemus, JS Reyes… - Biochemical Society …, 2023 - portlandpress.com
The pentose phosphate pathway (PPP) is a key metabolic pathway. The oxidative phase of
this process involves three reactions catalyzed by glucose-6-phosphate dehydrogenase …
this process involves three reactions catalyzed by glucose-6-phosphate dehydrogenase …
COVID-19 and Alzheimer's Disease Share Common Neurological and Ophthalmological Manifestations: A Bidirectional Risk in the Post-Pandemic Future
G Amadoro, V Latina, E Stigliano, A Micera - Cells, 2023 - mdpi.com
A growing body of evidence indicates that a neuropathological cross-talk takes place
between the coronavirus disease 2019 (COVID-19)-the pandemic severe pneumonia that …
between the coronavirus disease 2019 (COVID-19)-the pandemic severe pneumonia that …
Mitochondrial vulnerability to oxidation in human brain organoids modelling Alzheimer's disease
MI Holubiec, M Alloatti, J Bianchelli, F Greloni… - Free Radical Biology …, 2023 - Elsevier
Abstract Reactive Oxygen Species (ROS) and mitochondrial dysfunction are implicated in
the pathogenesis of Alzheimer's disease (AD), a common neurodegenerative disorder …
the pathogenesis of Alzheimer's disease (AD), a common neurodegenerative disorder …
Mitochondrial Complex I and β-Amyloid Peptide Interplay in Alzheimer's Disease: A Critical Review of New and Old Little Regarded Findings
Alzheimer's disease (AD) is the most common neurodegenerative disorder and the main
cause of dementia which is characterized by a progressive cognitive decline that severely …
cause of dementia which is characterized by a progressive cognitive decline that severely …