One of the greatest challenges of humanity for deep space exploration is to fully understand
how altered gravitational conditions affect human physiology. It is evident that the spaceflight …

Due to the increased crewed spaceflights in recent years, it is vital to understand how the
space environment affects human health. A lack of gravitational force is known to risk …

Microgravity changes the gene expression pattern in various cell types. This study focuses
on the breast cancer cell lines MCF-7 (less invasive) and MDA-MB-231 (triple-negative …

Impairment of the central nervous system (CNS) poses a significant health risk for astronauts
during long-duration space missions. In this study, we employed an innovative approach by …

A detailed understanding of how spaceflight affects human health is essential for long-term
space exploration. Liquid biopsies allow for minimally-invasive multi-omics assessments …

Impairment of the central nervous system (CNS) functions in astronauts is a major health risk
for long-duration space missions. Here, for the first time, we combine single-cell multiomics …

During space travel, microgravity leads to disturbances in cognitive function, while the
underlying mechanism is still unclear. Simulated microgravity mice showed neuronal age …

Prolonged spaceflight can induce physiologic and pathologic abnormalities in the central
nervous system (CNS). Our knowledge of the adaptive and/or detrimental effects of …

The grueling psychological demands of a journey into deep space coupled with ever-
increasing distances away from home pose a unique problem: how can we best take …

Introduction: Microgravity (MG) exposure causes motor deficits and decreased neuronal
activity, effects that resemble the ones observed in motor neuron diseases such as …