Cytotoxic meroterpenoids from brown alga Stypopodium schimperi (Kützing) Verlaque & Boudouresque with comprehensive molecular docking & dynamics and …

Ö Demirkıran, E Erol, H Şenol, İM Kesdi… - Process …, 2024 - Elsevier
In this study, five known meroterpenoids sargaol (1), flabellinone (2), stypodiol (3),
atomarianone A (4), atomarianone B (5), and a known steroid fucosterol (6) were isolated …

Novel chalcone derivatives of ursolic acid as acetylcholinesterase inhibitors: Synthesis, characterization, biological activity, ADME prediction, molecular docking and …

H Şenol, M Ghaffari-Moghaddam, GÖA Toraman… - Journal of Molecular …, 2024 - Elsevier
Acetylcholinesterase (AChE) is a critical target in the prevention of Alzheimer's Disease (AD)
progression. With the goal of developing potential acetylcholinesterase inhibitors, a new …

3‐Amino‐thiophene‐2‐carbohydrazide Derivatives as Anti Colon Cancer Agents: Synthesis, Characterization, In‐Silico and In‐Vitro Biological Activity Studies

H Şenol, F Çakır - ChemistrySelect, 2023 - Wiley Online Library
In this study, starting from 3‐amino‐thiophene‐2‐carboxylic acid methyl ester, eighteen new
arylidenehydrazide derivatives (4–21) were synthesized. To determine cytotoxic activity of …

[PDF][PDF] Synthesis and anticancer activity of novel derivatives of α, β‐unsaturated ketones based on oleanolic acid: in vitro and in silico studies against prostate cancer …

H Şenol, M Ghaffari-Moghaddam, Ş Bulut, F Akbaş… - 2023 - openaccess.bezmialem.edu.tr
Herein, new derivatives of α, β-unsaturated ketones based on oleanolic acid (4 ai) were
designed, synthesized, characterized, and tested against human prostate cancer (PC3) …

New tetrahydro-isoquinoline derivatives as cholinesterase and α-glycosidase inhibitors: Synthesis, characterization, molecular docking & dynamics, ADME prediction …

I Mamedov, H Şenol, F Naghiyev, V Khrustalev… - Journal of Molecular …, 2024 - Elsevier
In the presented work, it was reported about the synthesis procedure of new isoquinoline
derivatives starting from chalcones and acetoacetanilide, a multi-step synthesis pathway …

Novel complex compounds of nickel with 3-(1-phenyl-2, 3-dimethyl-pyrazolone-5) azopentadione-2, 4: synthesis, NBO analysis, reactivity descriptors and in silico and …

S Tahirli, F Aliyeva, H Şenol… - Journal of …, 2024 - Taylor & Francis
A synthesized azo compound based on 4-amino antipyrine and its complexes with Ni (II) in
solution and solid phase is reported. The structures of these compounds have been testified …

Synthesis, Characterization, Crystal Structure, Molecular dynamics simulations, MM-GBSA analysis, and Bioactivity studies of pyrazine-and Pyrimidine-Modulated …

GG Abbasova, RH Ismayilov, DB Tagiyev… - Journal of Molecular …, 2024 - Elsevier
By using unsymmetrical pyrazine-and pyrimidine-modulated oligo-α-pyridylamine ligand N-
(4-methylpyrimidin-2-yl) pyrazin-2-amine (Hmpmpza)(1), 1D copper (II) coordination …

4‐Furfuryloxymethyl‐1, 2, 3‐triazol‐1‐yl‐acetohydrazide Hybrids as Cholinesterase and Carbonic Anhydrase Inhibitors: Synthesis, Characterization and …

H Şenol - ChemistrySelect, 2024 - Wiley Online Library
This study focused on the synthesis and evaluation of the biological activity of ten novel
acetohydrazide hybrid derivatives, having furfuryloxy‐1, 2, 3‐triazole ring. All the target …

Nipagin Türevi Yeni Hidrazonların Sentezi ve in Siliko Biyolojik Etkinliklerinin Belirlenmesi

H ŞENOL - Journal of the Institute of Science and Technology, 2023 - dergipark.org.tr
Bu çalışmada nipagin'den (metil paraben, metil-4-hidroksibenzoat) hareketle yeni seçici ve
düşük toksisiteye sahip potansiyel anti kanser ajanlar geliştirilmesi amacıyla arilidenhidrazid …

Antioxidant properties and aldose reductase inhibitory potency of Viscum album L. extracts: experimental and computational insights

B Akyüz, B Şengül - Turkish Journal of Agriculture and …, 2024 - journals.tubitak.gov.tr
This study systematically investigates the antioxidant capacity and inhibitory impact of
Viscum album L. plant extracts on the aldose reductase (AR) enzyme through a combined …