Understanding NAFLD: from case identification to interventions, outcomes, and future perspectives

D Clayton-Chubb, W Kemp, A Majeed, JS Lubel… - Nutrients, 2023 - mdpi.com
While non-alcoholic fatty liver disease (NAFLD) is a prevalent and frequent cause of liver-
related morbidity and mortality, it is also strongly associated with cardiovascular disease …

The interplay between oral microbiota, gut microbiota and systematic diseases

X Tan, Y Wang, T Gong - Journal of Oral Microbiology, 2023 - Taylor & Francis
Over the past two decades, the importance of microbiota in health and disease has become
evident. The human gut microbiota and oral microbiota are the largest and second-largest …

Age-related NAFLD: The use of probiotics as a supportive therapeutic intervention

LIM Campagnoli, N Marchesi, M Vairetti, A Pascale… - Cells, 2022 - mdpi.com
Human aging, a natural process characterized by structural and physiological changes,
leads to alterations of homeostatic mechanisms, decline of biological functions, and …

Utility of human relevant preclinical animal models in navigating NAFLD to MAFLD paradigm

D Chua, ZS Low, GX Cheam, AS Ng… - International Journal of …, 2022 - mdpi.com
Fatty liver disease is an emerging contributor to disease burden worldwide. The past
decades of work established the heterogeneous nature of non-alcoholic fatty liver disease …

Fructooligosaccharides and galactooligosaccharides improve hepatic steatosis via gut microbiota-brain axis modulation

RS Silva, IP Mendonça, IHR Paiva… - … Journal of Food …, 2023 - Taylor & Francis
Studies have shown that gut dysbiosis is associated with the steatotic liver disease
associated with metabolic dysfunction (MALSD) and its severity. This study evaluated the …

Gut microbiota-derived indole compounds attenuate metabolic dysfunction-associated steatotic liver disease by improving fat metabolism and inflammation

BH Min, S Devi, GH Kwon, H Gupta, JJ Jeong… - Gut …, 2024 - Taylor & Francis
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common
chronic liver disease, and its prevalence has increased worldwide in recent years …

Membrane Vesicles of Toxigenic Clostridioides difficile Affect the Metabolism of Liver HepG2 Cells

E Caballano-Infantes, A Ho-Plágaro, C López-Gómez… - Antioxidants, 2023 - mdpi.com
Clostridioides difficile infection (CDI) appears to be associated with different liver diseases.
C. difficile secretes membrane vesicles (MVs), which may be involved in the development of …

Impact of adherence to the Mediterranean diet on antioxidant status and metabolic parameters in Nafld patients: A 24-month lifestyle intervention study

MM Quetglas-Llabrés, M Monserrat-Mesquida… - Antioxidants, 2024 - mdpi.com
Background: The Mediterranean Diet (MedDiet) is recognized as a healthy dietary pattern.
Non-alcoholic fatty liver disease (NAFLD) is characterized by the excessive accumulation of …

NASH/NAFLD-Related Hepatocellular Carcinoma: An Added Burden

D Georgescu, DF Lighezan, CI Rosca, D Nistor… - Life, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) is the most frequently found primary malignancy of the
liver, showing an accelerated upward trend over the past few years and exhibiting an …

Diagnostic scores and scales for appraising Nonalcoholic fatty liver disease and omics perspectives for precision medicine

N Perez-Diaz-del-Campo… - Current Opinion in …, 2022 - journals.lww.com
The growing NAFLD pandemic urges clinicians to seek alternatives for screening, early
diagnosis, and follow-up, especially for those with contraindications for liver biopsy. New …