Neurotrophic factors-based therapeutic strategies in the spinal cord injury: an overview of recent preclinical studies in rodent models

N Deznabi, S Hosseini, M Rajabi - The Egyptian Journal of Neurology …, 2023 - Springer
Following the traumatic spinal cord injury (SCI) and initial mechanical insult, a cascade of
secondary cellular and molecular events occurs at the trauma site. This phenomenon …

Cerebrolysin® and environmental enrichment, alone or in combination, ameliorate anxiety-and depressive-like behaviors in a post-ischemic depression model in mice

F Farajdokht, F Oghbaei, S Sadigh-Eteghad… - Journal of Stroke and …, 2022 - Elsevier
Objectives This study examined the beneficial effects of cerebrolysin (CBL) and enriched
environment (EE), alone or in combination, on the neurobehavioral and molecular changes …

Synergistic effects of combined therapy with cerebrolysin and enriched environment on anxiety-like behavior and spatial cognitive deficits in posttraumatic stress …

L Hosseini, S Sadigh-Eteghad… - Behavioural …, 2023 - journals.lww.com
Posttraumatic stress disorder (PTSD) is a serious neuropsychiatric disorder that occurs after
exposure to stressful, fearful, or troubling events. Cerebrolysin (CBL), consists of low …

Telmisartan inhibits bladder smooth muscle fibrosis in neurogenic bladder rats

Q Liu, R Wang, N Ma, C Wang… - Experimental and …, 2022 - spandidos-publications.com
Hypertension is associated with bladder symptoms. The present study investigated whether
an angiotensin receptor blocker could improve the symptoms and pathological changes …

Change in the central control of the bladder function of rats with focal cerebral infarction induced by photochemically-induced thrombosis

Y Ota, Y Kubota, Y Hotta, M Matsumoto, N Matsuyama… - Plos one, 2021 - journals.plos.org
The photochemically-induced thrombosis (photothrombosis) method can create focal
cerebral infarcts anywhere in the relatively superficial layers of the cerebrum; it is easy to …

[HTML][HTML] Human Mesenchymal Stem Cell Transplantation Improved Functional Outcomes Following Spinal Cord Injury Concomitantly with Neuroblast Regeneration

ML Ataei, M Karimipour, P Shahabi… - Advanced …, 2023 - ncbi.nlm.nih.gov
Purpose: Spinal cord injury (SCI) is damage to the spinal cord that resulted in irreversible
neuronal loss, glial scar formation and axonal injury. Herein, we used the human amniotic …

A comprehensive visual report of urodynamic study in rats with spinal cord injury

H Salehi-Pourmehr, J Mahmoudi, AS Vahdat… - Current …, 2022 - journals.lww.com
Objectives Spinal cord injury (SCI) is one of the most debilitating and expensive traumatic
conditions. Chronic complications after SCI have a particularly negative impact on patients' …

The Potential Therapeutic Effect of Cerebrolysin against Cyclosporine A-Induced Cerebellar Toxicity in Adult Male Albino Rats

H Arafat, G Refaat, M Awny, E Fekry - Mansoura Journal of Forensic …, 2024 - journals.ekb.eg
Background: Cyclosporin A is an immunosuppressive agent used to treat organ rejection
post-transplant and autoimmune diseases. It can induce toxic effects on the cerebellar cortex …

Cerebrolysin Use in Stroke and Spinal Cord Injury: Review of the Literature and Outcomes

N Abolhasanpour, P Sadeghi, M Gholizadeh… - International Journal of …, 2023 - ijdrug.com
Cerebrolysin (CBL) is a porcine brain-derived preparation with noticeable neurotrophic and
neuroprotective activity. Treatment with CBL has significant potential to treat various …

Change in the bladder function of rats with focal cerebral infarction induced by photochemically-induced thrombosis

Y Ota, Y Kubota, Y Hotta, M Matsumoto, N Matsuyama… - bioRxiv, 2021 - biorxiv.org
The photochemically-induced thrombosis (photothrombosis) method can create focal
cerebral infarcts anywhere in the relatively superficial layers of the cerebrum; it is easy to …