Recent studies have revealed the vital role of MSCs in bone regeneration. In both self-
healing bone regeneration processes and biomaterial-induced healing of bone defects …

Aims Retinal age derived from fundus images has been verified as a novel ageing
biomarker. We aim to explore the association between retinal age gap (retinal age minus …

Background Pyroptosis of retinal pigment epithelium (RPE) cells is associated with the
etiology of diabetic retinopathy (DR). In this study, we investigated the effect of DNMT1 on …

There is growing evidence that retinal degenerative diseases are accompanied by
epigenetic changes in both deoxyribonucleic acid methylation and histone modification …

Graphene quantum dots (GQDs) are used in diverse fields from chemistry-related materials
to biomedicines, thus causing their substantial release into the environment. Appropriate …

Purpose DNA methylation is involved in Diabetic Retinopathy progression showing a
metabolic memory mechanism. However, the association of DNA methyltransferase with …

Oxidative stress forms part of the molecular basis contributing to the development and
manifestation of myopia, a refractive error with associated pathology that is increasingly …

Purpose: Choroidal neovascularization (CNV) can constitute the final pathology of many
ocular diseases and result in severe vision loss. Studies have demonstrated that DNA …

Background Diabetic retinopathy (DR) is a common and serious microvascular complication
of diabetes mellitus (DM), but its pathological mechanism, especially the formation …

We explored differences in the DNA methylation statuses of PSMA6, PSMB5, HIF1A, and
KEAP1 gene promoter regions in patients with type 1 diabetes and different diabetic …