Molecular self‐assembly is central to many processes in both biology and supramolecular
chemistry. The G‐quartet, a hydrogen‐bonded macrocycle formed by cation‐templated …

Guanine-rich DNA sequences can form G-quadruplexes stabilized by stacked G–G–G–G
tetrads in monovalent cation-containing solution. The length and number of individual G …

Over the past decade, nucleic acid chemists have seen the spectacular emergence of
molecules designed to interact efficiently and selectively with a peculiar DNA structure …

G‐quadruplexes are special secondary structures adopted in some guanine‐rich DNA
sequences. As guanine‐rich sequences are present in important regions of the eukaryotic …

Herein, we report the design, synthesis, biophysical evaluation with primary biological data
of 3, 8, 10-trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands. We …

A G-Quadruplex Ligand with 10000-Fold Selectivity over Duplex DNA | Journal of the American
Chemical Society ACS ACS Publications C&EN CAS Find my institution Log In Journal of the …

Regulation of the transcription machinery is one of the many ways to achieve control of gene
expression. This has been done either at the transcription initiation stage or at the …

Die molekulare Selbstorganisation spielt bei vielen Prozessen in der Biologie und der
Supramolekularen Chemie eine zentrale Rolle. Das G‐Quartett, ein durch …

We report bis-phenylethynyl amide derivatives as a potent G-quadruplex binding small
molecule scaffold. The amide derivatives were efficiently prepared in 3 steps by employing …

New cyanines were prepared by an efficient and practical route with satisfactory overall yield
from low-cost starting materials. The photophysical behavior of the cyanines was …