Crossing the blood-brain barrier: advances in nanoparticle technology for drug delivery in neuro-oncology
The blood-brain barrier (BBB) constitutes a microvascular network responsible for excluding
most drugs from the brain. Treatment of brain tumors is limited by the impermeability of the …
most drugs from the brain. Treatment of brain tumors is limited by the impermeability of the …
Applications and limitations of dendrimers in biomedicine
Biomedicine represents one of the main study areas for dendrimers, which have proven to
be valuable both in diagnostics and therapy, due to their capacity for improving solubility …
be valuable both in diagnostics and therapy, due to their capacity for improving solubility …
Dendrimers: A versatile nanocarrier for drug delivery and targeting
Dendrimers are novel polymeric nanoarchitectures characterized by hyper-branched 3D-
structure having multiple functional groups on the surface that increases their functionality …
structure having multiple functional groups on the surface that increases their functionality …
Intestinal absorption study: Challenges and absorption enhancement strategies in improving oral drug delivery
M Azman, AH Sabri, QK Anjani, MF Mustaffa… - Pharmaceuticals, 2022 - mdpi.com
The oral route is the most common and practical means of drug administration, particularly
from a patient's perspective. However, the pharmacokinetic profile of oral drugs depends on …
from a patient's perspective. However, the pharmacokinetic profile of oral drugs depends on …
Dendrimers in drug delivery and targeting: Drug-dendrimer interactions and toxicity issues
Dendrimers are the emerging polymeric architectures that are known for their defined
structures, versatility in drug delivery and high functionality whose properties resemble with …
structures, versatility in drug delivery and high functionality whose properties resemble with …
Dendrimers designed for functions: from physical, photophysical, and supramolecular properties to applications in sensing, catalysis, molecular electronics, photonics …
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular
Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and …
Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and …
Dendrimer-based drug delivery systems for brain targeting
Y Zhu, C Liu, Z Pang - Biomolecules, 2019 - mdpi.com
Human neuroscience has made remarkable progress in understanding basic aspects of
functional organization; it is a renowned fact that the blood–brain barrier (BBB) impedes the …
functional organization; it is a renowned fact that the blood–brain barrier (BBB) impedes the …
Dendrimers in biomedical applications—reflections on the field
S Svenson, DA Tomalia - Advanced drug delivery reviews, 2012 - Elsevier
The formation of particulate systems with well-defined sizes and shapes is of eminent
interest in certain medical applications such as drug delivery, gene transfection, and …
interest in certain medical applications such as drug delivery, gene transfection, and …
Dendrimer biocompatibility and toxicity
R Duncan, L Izzo - Advanced drug delivery reviews, 2005 - Elsevier
The field of biomedical dendrimers is still in its infancy, but the explosion of interest in
dendrimers and dendronised polymers as inherently active therapeutic agents, as vectors …
dendrimers and dendronised polymers as inherently active therapeutic agents, as vectors …
Nanostructured materials for applications in drug delivery and tissue engineering
Research in the areas of drug delivery and tissue engineering has witnessed tremendous
progress in recent years due to their unlimited potential to improve human health …
progress in recent years due to their unlimited potential to improve human health …