Crossing the blood-brain barrier: advances in nanoparticle technology for drug delivery in neuro-oncology

AM Hersh, S Alomari, BM Tyler - International journal of molecular …, 2022 - mdpi.com
The blood-brain barrier (BBB) constitutes a microvascular network responsible for excluding
most drugs from the brain. Treatment of brain tumors is limited by the impermeability of the …

Applications and limitations of dendrimers in biomedicine

AA Chis, C Dobrea, C Morgovan, AM Arseniu, LL Rus… - Molecules, 2020 - mdpi.com
Biomedicine represents one of the main study areas for dendrimers, which have proven to
be valuable both in diagnostics and therapy, due to their capacity for improving solubility …

Dendrimers: A versatile nanocarrier for drug delivery and targeting

AP Sherje, M Jadhav, BR Dravyakar… - International journal of …, 2018 - Elsevier
Dendrimers are novel polymeric nanoarchitectures characterized by hyper-branched 3D-
structure having multiple functional groups on the surface that increases their functionality …

Intestinal absorption study: Challenges and absorption enhancement strategies in improving oral drug delivery

M Azman, AH Sabri, QK Anjani, MF Mustaffa… - Pharmaceuticals, 2022 - mdpi.com
The oral route is the most common and practical means of drug administration, particularly
from a patient's perspective. However, the pharmacokinetic profile of oral drugs depends on …

Dendrimers in drug delivery and targeting: Drug-dendrimer interactions and toxicity issues

K Madaan, S Kumar, N Poonia, V Lather… - Journal of Pharmacy …, 2014 - journals.lww.com
Dendrimers are the emerging polymeric architectures that are known for their defined
structures, versatility in drug delivery and high functionality whose properties resemble with …

Dendrimers designed for functions: from physical, photophysical, and supramolecular properties to applications in sensing, catalysis, molecular electronics, photonics …

D Astruc, E Boisselier, C Ornelas - Chemical reviews, 2010 - ACS Publications
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular
Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and …

Dendrimer-based drug delivery systems for brain targeting

Y Zhu, C Liu, Z Pang - Biomolecules, 2019 - mdpi.com
Human neuroscience has made remarkable progress in understanding basic aspects of
functional organization; it is a renowned fact that the blood–brain barrier (BBB) impedes the …

Dendrimers in biomedical applications—reflections on the field

S Svenson, DA Tomalia - Advanced drug delivery reviews, 2012 - Elsevier
The formation of particulate systems with well-defined sizes and shapes is of eminent
interest in certain medical applications such as drug delivery, gene transfection, and …

Dendrimer biocompatibility and toxicity

R Duncan, L Izzo - Advanced drug delivery reviews, 2005 - Elsevier
The field of biomedical dendrimers is still in its infancy, but the explosion of interest in
dendrimers and dendronised polymers as inherently active therapeutic agents, as vectors …

Nanostructured materials for applications in drug delivery and tissue engineering

M Goldberg, R Langer, X Jia - Journal of Biomaterials Science …, 2007 - Taylor & Francis
Research in the areas of drug delivery and tissue engineering has witnessed tremendous
progress in recent years due to their unlimited potential to improve human health …