The role of machine learning in healthcare responses to pandemics: maximizing benefits and filling gaps

AZ Al Meslamani, AS Jarab… - Journal of Medical …, 2023 - Taylor & Francis
Full article: The role of machine learning in healthcare responses to pandemics: maximizing
benefits and filling gaps Skip to Main Content Taylor and Francis Online homepage Browse …

KUALA: A machine learning-driven framework for kinase inhibitors repositioning

G De Simone, DS Sardina, MR Gulotta, U Perricone - Scientific Reports, 2022 - nature.com
The family of protein kinases comprises more than 500 genes involved in numerous
functions. Hence, their physiological dysfunction has paved the way toward drug discovery …

Fedpia: Parameter importance-based optimized federated learning to efficiently process non-iid data on consumer electronic devices

Y Zeng, Y Yin, J Zhang, M Xue… - IEEE Transactions on …, 2023 - ieeexplore.ieee.org
Federated learning is a distributed machine learning method for learning consumer data
generated by consumer electronic devices. It provides personalized intelligent services for …

Machine learning and biological evaluation-based identification of a potential MMP-9 inhibitor, effective against ovarian cancer cells SKOV3

K Sinha, S Parwez, S Mv, A Yadav… - Journal of …, 2023 - Taylor & Francis
MMP-9, also known as gelatinase B, is a zinc-metalloproteinase family protein that plays a
key role in the degradation of the extracellular matrix (ECM). The normal function of MMP-9 …

Recent applications of bioinformatics in target identification and drug discovery for Alzheimer's disease

SK Singh, A Kumar, RB Singh… - Current topics in …, 2022 - ingentaconnect.com
Alzheimer's disease (AD) is a complex multifactorial neurodegenerative disease
characterized by progressive memory loss. The main pathological features of the disease …

[HTML][HTML] Drug repurposing on Alzheimer's disease through modulation of NRF2 neighborhood

MM Bourdakou, R Fernández-Ginés, A Cuadrado… - Redox Biology, 2023 - Elsevier
Alzheimer's disease (AD) is an age-dependent neurodegenerative disorder and the most
common cause of cognitive decline. The alarming epidemiological features of Alzheimer's …

On calibration of graph neural networks for node classification

T Liu, Y Liu, M Hildebrandt, M Joblin… - … Joint Conference on …, 2022 - ieeexplore.ieee.org
Graphs can model real-world, complex systems by representing entities and their
interactions in terms of nodes and edges. To better exploit the graph structure, graph neural …

Healthcare knowledge graph construction: State-of-the-art, open issues, and opportunities

B Abu-Salih, M Al-Qurishi, M Alweshah… - arXiv preprint arXiv …, 2022 - arxiv.org
The incorporation of data analytics in the healthcare industry has made significant progress,
driven by the demand for efficient and effective big data analytics solutions. Knowledge …

Transcriptome-based deep learning analysis identifies drug candidates targeting protein synthesis and autophagy for the treatment of muscle wasting disorder

MH Lee, B Lee, SE Park, GE Yang, S Cheon… - … & Molecular Medicine, 2024 - nature.com
Sarcopenia, the progressive decline in skeletal muscle mass and function, is observed in
various conditions, including cancer and aging. The complex molecular biology of …

Anthelmintic Drugs as Emerging Immune Modulators in Cancer

C Stolfi, T Pacifico, A Luiz-Ferreira… - International Journal of …, 2023 - mdpi.com
Despite recent advances in treatment approaches, cancer is still one of the leading causes
of death worldwide. Restoration of tumor immune surveillance represents a valid strategy to …