version of the Guidelines, which is freely available via the ESC and EAS websites and
hosted on their journals' websites (EHJ and Atherosclerosis Journal). The National Cardiac …

Aims To objectively appraise evidence for possible adverse effects of long-term statin
therapy on glucose homeostasis, cognitive, renal and hepatic function, and risk for …

5.1. Wpływ stylu życia na stężenie cholesterolu całkowitego i stężenie cholesterolu frakcji
lipoprotein o małej gęstości................................ 1259 5.2. Wpływ stylu życia na stężenie …

A systematic review of cohort studies, randomized trials, voluntary notifications to national
regulatory authorities, and published case reports was undertaken to assess the incidence …

The content of these European Society of Cardiology (ESC) and European Atherosclerosis
Society Guidelines has been published for personal and educational use only. No …

Serious adverse drug reactions (SADRs) are a major cause of morbidity and mortality
worldwide. Some SADRs may be predictable, based upon a drug's pharmacodynamic and …

Patients with chronic kidney disease (CKD) are much more likely to die of cardiovascular
disease than end-stage renal disease. Dyslipidemia is highly prevalent in patients with CKD …

Data from recent clinical trials of high-versus moderate-dose statin therapy support the
recommendation to achieve a low-density lipoprotein (LDL)< 100 mg/dl in high-risk patients …

Study Objective. To characterize the properties and natural history of 3–hydroxy‐3‐
methylglutaryl coenzyme A reductase inhibitor (statin)‐associated muscle‐related adverse …

Rosuvastatin is a fully synthetic statin wich acts by interfering with the endogenous synthesis
of cholesterol through competitively inhibiting the 3-hydroxy-3-methylglutaryl coenzyme A …