Statin use can be accompanied by a variety of musculoskeletal complaints. The authors
describe the clinical characteristics of case patients who experienced adverse statin …

aBsTRaCT The placebo-corrected incidence of rhabdomyolysis in a systematic review of 20
statin trials was 1.6/100,000 per year. It is likely to be higher than this in everyday clinical …

Simvastatin is one of the most commonly prescribed CoA reductase inhibitors. The safety
profile of this drug has been widely discussed in the medical and consumer advocacy …

Statins are among the most frequently issued drugs that patients usually need to take for a
lifetime. They are often an integral part of a polytherapeutic approach in preventing and …

Background: There is an increasing body of evidence to support the benefits of reducing low-
density lipoprotein cholesterol (LDL-C) levels and this has been reflected in a lowering of …

The JUPITER trial (Justification for the Use of Statins in Prevention: an Intervention Trial
Evaluating Rosuvastatin)(N Engl J Med 2008; 359: 2195–2207) compared rosuvastatin …

The most recent guidelines of the National Cholesterol Education Program recommend
more aggressive low‐density lipoprotein cholesterol goals:< 100 mg/dL for patients at …

Coronary heart disease (CHD) is the leading cause of death worldwide. The efficacy and
safety of statins in primary and secondary prevention of CHD is confirmed in several large …

Abstract Background/Aims: Statins are prescribed in kidney transplant recipients in order to
manage dyslipidemia, a common complication in these patients. The efficacy of statins in …

Rheumatoid arthritis, a chronic inflammatory polyarthritis that destroys synovial joints, is
associated with systemic as well as local inflammation and with an increased risk of …