Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease that can
potentially lead to serious organ complications and even death. Its global burden—in terms …

Objective This chapter aims to evaluate current knowledge of the burden of systemic lupus
erythematosus (SLE) on individual patients, with a particular focus on health-related quality …

Pain is a prominent component of many rheumatologic conditions, and is the result of a
complex physiologic interaction of central and peripheral nervous system signaling that …

Purpose To determine the association between the number of flares systemic lupus
erythematosus (SLE) patients experience and damage accrual, independently of other …

Systemic Lupus Erythematosus (SLE) is a complex chronic autoimmune disease that
manifests a wide range of organ involvement. Traditionally, the diagnosis and management …

Fatigue is one of the most complex and ill understood symptoms of chronic illness often
reported as the number one complaint by patients with systemic lupus erythematosus (SLE) …

Comorbidities and multimorbidity, often complicating the disease course of patients with
chronic inflammatory rheumatic diseases, may be influenced by disease-intrinsic and …

Objective To examine the burden of systemic lupus erythematosus (SLE) on work loss,
unemployment, and work productivity impairment in an SLE cohort from the southeastern …

Introduction: Patients with systemic lupus erythematosus (SLE) have a better survival than
decades ago; nevertheless, they still experience a low health-related (HR) quality of life …

Formidable impediments stand in the way of treatment development for lupus. These include
the unwieldy size of current trials, international competition for scarce patients, complex …