Functional Potassium Channels in Macrophages

Q Man, Z Gao, K Chen - The Journal of Membrane Biology, 2023 - Springer
Macrophages are the predominant component of innate immunity, which is an important
protective barrier of our body. Macrophages are present in all organs and tissues of the …

Excitotoxic Storms of Ischemic Stroke: A Non-neuronal Perspective

X Yang, H Yu, J Li, N Li, C Li, D Xu, H Zhang… - Molecular …, 2024 - Springer
Numerous neurological disorders share a fatal pathologic process known as glutamate
excitotoxicity. Among which, ischemic stroke is the major cause of mortality and disability …

[HTML][HTML] Validation of TREK1 ion channel activators as an immunomodulatory and neuroprotective strategy in neuroinflammation

CB Schroeter, C Nelke, M Schewe, L Spohler… - Biological …, 2023 - degruyter.com
Modulation of two-pore domain potassium (K2P) channels has emerged as a novel field of
therapeutic strategies as they may regulate immune cell activation and metabolism …

Kv7 channel activation reduces brain endothelial cell permeability and prevents kainic acid-induced blood-brain barrier damage

C Celentano, L Carotenuto, F Miceli… - … of Physiology-Cell …, 2024 - journals.physiology.org
Ion channels in the blood-brain barrier (BBB) play a main role in controlling the interstitial
fluid composition and cerebral blood flow, and their dysfunction contributes to the disruption …

[PDF][PDF] 孤独症谱系障碍小鼠肠道屏障功能研究

刘思濛, 席华媛, 孙向东, 郑瑞娟, 赵锐豪… - 中国微生态学 …, 2023 - cjm.dmu.edu.cn
目的研究孤独症谱系障碍(ASD) 模型小鼠肠道屏障功能及肠道动力的改变情况, 为微生物− 肠−
脑轴在ASD 发病中的作用提供理论基础. 方法C57bl/6J 雌鼠和雄鼠交配, 丙戊酸钠(VPA) …