[HTML][HTML] Reactive oxygen species and antioxidant defense in human gastrointestinal diseases

P Patlevič, J Vašková, P Švorc Jr, L Vaško… - Integrative medicine …, 2016 - Elsevier
Crohn's disease and ulcerative colitis, known together as inflammatory bowel diseases
(IBDs), and celiac disease are the most common disorders affecting not only adults but also …

[HTML][HTML] Mucosal interactions between genetics, diet, and microbiome in inflammatory bowel disease

A Basson, A Trotter, A Rodriguez-Palacios… - Frontiers in …, 2016 - frontiersin.org
Numerous reviews have discussed gut microbiota composition changes during inflammatory
bowel diseases (IBD), particularly Crohn's disease (CD). However, most studies address the …

Intergenerational transfer of antibiotic-perturbed microbiota enhances colitis in susceptible mice

AF Schulfer, T Battaglia, Y Alvarez, L Bijnens… - Nature …, 2018 - nature.com
Antibiotic exposure in children has been associated with the risk of inflammatory bowel
disease (IBD). Antibiotic use in children or in their pregnant mother can affect how the …

Modulation of the microbiota-gut-brain axis by probiotics in a murine model of inflammatory bowel disease

JR Emge, K Huynh, EN Miller, M Kaur… - American Journal …, 2016 - journals.physiology.org
Anxiety, depression, and altered memory are associated with intestinal diseases, including
inflammatory bowel disease (IBD). Understanding the link between these behavioral …

[HTML][HTML] Implications of antioxidant systems in inflammatory bowel disease

G Guan, S Lan - BioMed research international, 2018 - hindawi.com
The global incidence of inflammatory bowel disease (IBD), a group of chronic
gastrointestinal disorders, has been rising. The preponderance of evidence demonstrates …

Protective and pro-inflammatory roles of intestinal bacteria

CR Webb, I Koboziev, KL Furr, MB Grisham - Pathophysiology, 2016 - Elsevier
The intestinal mucosal surface in all vertebrates is exposed to enormous numbers of
microorganisms that include bacteria, archaea, fungi and viruses. Coexistence of the host …

[PDF][PDF] The xenobiotic transporter Mdr1 enforces T cell homeostasis in the presence of intestinal bile acids

W Cao, H Kayama, ML Chen, A Delmas, A Sun, SY Kim… - Immunity, 2017 - cell.com
CD4+ T cells are tightly regulated by microbiota in the intestine, but whether intestinal T cells
interface with host-derived metabolites is less clear. Here, we show that CD4+ T effector …

DSS-induced colitis produces inflammation-induced bone loss while irisin treatment mitigates the inflammatory state in both gut and bone

CE Metzger, SA Narayanan, JP Elizondo, AM Carter… - Scientific Reports, 2019 - nature.com
Chronic pediatric inflammatory bowel disease (IBD) leads to lack of bone accrual, bone loss,
and increased fractures. Presently there is no cure, and many IBD treatments incur negative …

[HTML][HTML] A Potential Role of Salmonella Infection in the Onset of Inflammatory Bowel Diseases

BM Schultz, CA Paduro, GA Salazar… - Frontiers in …, 2017 - frontiersin.org
Inflammatory bowel disease (IBD) includes a set of pathologies that result from a
deregulated immune response that may affect any portion of the gastrointestinal tract. The …

The molecular biology of matrix metalloproteinases and tissue inhibitors of metalloproteinases in inflammatory bowel diseases

M De Bruyn, J Vandooren, E Ugarte-Berzal… - Critical Reviews in …, 2016 - Taylor & Francis
Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) are
thought to be predominant proteases and protease inhibitors involved in the pathogenesis of …