Cisplatin mouse models: Treatment, toxicity and translatability

M Perše - Biomedicines, 2021 - mdpi.com
Cisplatin is one of the most widely used chemotherapeutic drugs in the treatment of a wide
range of pediatric and adult malignances. However, it has various side effects which limit its …

[PDF][PDF] Cisplatin for cancer therapy and overcoming chemoresistance

R Ranasinghe, ML Mathai, A Zulli - Heliyon, 2022 - cell.com
Cisplatin spearheads the anticancer chemotherapeutics in present-day use although acute
toxicity is its primary impediment factor. Among a plethora of experimental medications, a …

[HTML][HTML] Nuclear farnesoid X receptor attenuates acute kidney injury through fatty acid oxidation

S Xu, P Jia, Y Fang, J Jin, Z Sun, W Zhou, J Li… - Kidney International, 2022 - Elsevier
Acute kidney injury (AKI) is a life-threatening condition that is one of most common side
effects of cisplatin therapy. Fatty acid oxidation (FAO) is the main source of energy …

Bioactive NIR-II gold clusters for three-dimensional imaging and acute inflammation inhibition

H Ma, X Zhang, L Liu, Y Huang, S Sun, K Chen… - Science …, 2023 - science.org
Strong fluorescence and high catalytic activities cannot be achieved simultaneously due to
conflicts in free electron utilization, resulting in a lack of bioactivity of most near-infrared-II …

[HTML][HTML] Tubular cell senescence promotes maladaptive kidney repair and chronic kidney disease after cisplatin nephrotoxicity

S Li, MJ Livingston, Z Ma, X Hu, L Wen, HF Ding… - JCI insight, 2023 - ncbi.nlm.nih.gov
Cisplatin is a widely used chemotherapy drug; however, it induces both acute and chronic
kidney diseases (CKD) in patients with cancer. The pathogenesis of cisplatin-induced CKD …

β-Hydroxybutyrate against Cisplatin-Induced acute kidney injury via inhibiting NLRP3 inflammasome and oxidative stress

S Luo, M Yang, Y Han, H Zhao, N Jiang, L Li… - International …, 2022 - Elsevier
Cisplatin, as a commonly used anticancer drug, can easily lead to acute kidney injury (AKI),
and has received more and more attention in clinical practice. β-hydroxybutyric acid (BHB) is …

[HTML][HTML] Emerging early diagnostic methods for acute kidney injury

Z Xiao, Q Huang, Y Yang, M Liu, Q Chen, J Huang… - Theranostics, 2022 - ncbi.nlm.nih.gov
Many factors such as trauma and COVID-19 cause acute kidney injury (AKI). Late AKI have
a very high incidence and mortality rate. Early diagnosis of AKI provides a critical therapeutic …

[HTML][HTML] Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury

J Zhang, ZL Luan, XK Huo, M Zhang… - … journal of biological …, 2023 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) is a pathological condition characterized by a rapid decrease in
glomerular filtration rate and nitrogenous waste accumulation during hemodynamic …

[HTML][HTML] Promising influences of caffeic acid and caffeic acid phenethyl ester against natural and chemical toxins: A comprehensive and mechanistic review

S Ehtiati, M Alizadeh, F Farhadi, K Khalatbari… - Journal of Functional …, 2023 - Elsevier
Caffeic acid (CA) and caffeic acid phenethyl ester (CAPE) are natural compounds that have
been found in various foods and plants. These compounds have attracted much attention in …

The effect of β-carotene, tocopherols and ascorbic acid as anti-oxidant molecules on human and animal in vitro/in vivo studies: A review of research design and …

K Miazek, K Beton, A Śliwińska, B Brożek-Płuska - Biomolecules, 2022 - mdpi.com
Prolonged elevated oxidative stress (OS) possesses negative effect on cell structure and
functioning, and is associated with the development of numerous disorders. Naturally …