Mechanical circulatory support devices for pediatric patients with congenital heart disease

SG Chopski, WB Moskowitz, RM Stevens… - Artificial …, 2017 - Wiley Online Library
The use of mechanical circulatory support (MCS) devices is a viable therapeutic treatment
option for patients with congestive heart failure. Ventricular assist devices, cavopulmonary …

[HTML][HTML] Role and Applications of Experimental Animal Models of Fontan Circulation

Z Jalal, E Langouet, N Dib, S Le-Quellenec… - Journal of Clinical …, 2024 - mdpi.com
Over the last four decades, the Fontan operation has been the treatment of choice for
children born with complex congenital heart diseases and a single-ventricle physiology …

[HTML][HTML] Computational fluid dynamic simulations of a cavopulmonary assist device for failing Fontan circulation

WCP Lin, MG Doyle, SL Roche, O Honjo… - The Journal of thoracic …, 2019 - Elsevier
Objectives Adult patients who have undergone the Fontan procedure are highly vulnerable
to gradual, progressive circulatory failure, and options to reverse this situation are few. A …

Cavopulmonary support with a microaxial pump for the failing Fontan physiology

J Zhu, H Kato, YY Fu, L Zhao, C Foreman… - ASAIO …, 2015 - journals.lww.com
The number of patients with the failing Fontan physiology is increasing. We tested a novel in
situ microaxial pump (Impella) to support the failing atrio-pulmonary Fontan circulation in an …

Creation of the Fontan circulation in sheep: a survival model

J Van Puyvelde, F Rega, T Minami… - Interactive …, 2019 - academic.oup.com
OBJECTIVES Patients with a single ventricle survive thanks to the Fontan palliation.
Nevertheless, there is a growing number of Fontan patients with progressive heart failure. To …

Pressure–flow experimental performance of new intravascular blood pump designs for Fontan patients

SG Chopski, CS Fox, ML Riddle, KL McKenna… - Artificial …, 2016 - Wiley Online Library
An intravascular axial flow pump is being developed as a mechanical cavopulmonary assist
device for adolescent and adult patients with dysfunctional F ontan physiology. Coupling …

Use of ventricular assist device in univentricular physiology: the role of lumped parameter models

A Di Molfetta, G Ferrari, S Filippelli, L Fresiello… - Artificial …, 2016 - Wiley Online Library
Failing single‐ventricle (SV) patients might benefit from ventricular assist devices (VADs) as
a bridge to heart transplantation. Considering the complex physiopathology of SV patients …

Physics-driven impeller designs for a novel intravascular blood pump for patients with congenital heart disease

SG Chopski, CS Fox, KL McKenna, ML Riddle… - Medical engineering & …, 2016 - Elsevier
Mechanical circulatory support offers an alternative therapeutic treatment for patients with
dysfunctional single ventricle physiology. An intravascular axial flow pump is being …

A numerical simulation comparing a cavopulmonary assist device and VA ECMO for failing Fontan support

PL Hsu, D Wang, C Ballard-Croft, D Xiao… - ASAIO …, 2017 - journals.lww.com
A cavopulmonary assist device (CPAD) has been developed for failing Fontan support. This
CPAD pumps blood from superior/inferior vena cavae (SVC/IVC) to pulmonary artery. In this …

[HTML][HTML] Study on the optimal elastic modulus of flexible blades for right heart assist device supporting patients with single-ventricle physiologies

T Chen, X Cheng, X Liu, H Zhang… - Frontiers in …, 2024 - frontiersin.org
Background Patients with single-ventricle physiologies continue to experience insufficient
circulatory power after undergoing palliative surgeries. This paper proposed a right heart …