2023 ACC/AHA/ACCP/HRS guideline for the diagnosis and management of atrial fibrillation: a report of the American College of Cardiology/American Heart …

JA Joglar, MK Chung, AL Armbruster, EJ Benjamin… - Circulation, 2024 - Am Heart Assoc
AIM The “2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial
Fibrillation” provides recommendations to guide clinicians in the treatment of patients with …

Thyroid hormone plays an important role in cardiac function: from bench to bedside

H Yamakawa, TS Kato, JY Noh, S Yuasa… - Frontiers in …, 2021 - frontiersin.org
Thyroid hormones (THs) are synthesized in the thyroid gland, and they circulate in the blood
to regulate cells, tissues, and organs in the body. In particular, they exert several effects on …

Potential anti-COVID-19 therapeutics that block the early stage of the viral life cycle: structures, mechanisms, and clinical trials

RA Al-Horani, S Kar, KF Aliter - International Journal of Molecular …, 2020 - mdpi.com
The ongoing pandemic of coronavirus disease-2019 (COVID-19) is being caused by severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The disease continues to present …

Potassium channel-driven bioelectric signalling regulates metastasis in triple-negative breast cancer

SL Payne, P Ram, DH Srinivasan, TT Le, M Levin… - …, 2022 - thelancet.com
Background There is a critical need to better understand the mechanisms that drive local cell
invasion and metastasis to develop new therapeutics targeting metastatic disease …

Pulmonary fibrosis related to amiodarone—is it a standard pathophysiological pattern? A case-based literature review

CE Budin, IG Cocuz, AH Sabău, R Niculescu, IR Ianosi… - Diagnostics, 2022 - mdpi.com
Amiodarone hydrochloride is an antiarrhythmic drug, with proven efficacy in prevention and
treatment of numerous arrhythmias, atrial fibrillation especially, or ventricular arrhythmias …

Mechanisms and management of thyroid disease and atrial fibrillation: Impact of atrial electrical remodeling and cardiac fibrosis

A Takawale, M Aguilar, Y Bouchrit, R Hiram - Cells, 2022 - mdpi.com
Atrial fibrillation (AF) is the most common cardiac arrhythmia associated with increased
cardiovascular morbidity and mortality. The pathophysiology of AF is characterized by …

Amiodarone in the COVID-19 era: treatment for symptomatic patients only, or drug to prevent infection?

F Sanchis-Gomar, CJ Lavie, DP Morin… - American Journal of …, 2020 - Springer
Amiodarone, one of the most widely prescribed antiarrhythmic drugs to treat both ventricular
and supraventricular arrhythmias, has been identified as a candidate drug for use against …

Reservoir Microneedle Patch Mitigates Postsurgical Atrial Fibrillation

W Wang, Y Chen, L Huang, Z Lu… - Advanced Functional …, 2024 - Wiley Online Library
Oral amiodarone for 3–6 months is commonly required for the prevention and treatment of
atrial fibrillation (AF) after surgical ablation of refractory AF. However, clinical data show that …

Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone

C Nunes, S Proença, G Ambrosini, D Pamies… - Frontiers in …, 2023 - frontiersin.org
For ethical, economical, and scientific reasons, animal experimentation, used to evaluate the
potential neurotoxicity of chemicals before their release in the market, needs to be replaced …

Single beta-blocker or combined amiodarone therapy in implantable cardioverter-defibrillator and cardiac resynchronization therapy—defibrillator patients: Insights …

F Wiedmann, H Ince, C Stellbrink, T Kleemann… - Heart Rhythm, 2023 - Elsevier
Background Because of its antiarrhythmic potency and due to the lack of alternatives,
amiodarone is often used for antiarrhythmic therapy in patients with implantable cardioverter …