Pigs have substantial potential as biomedical models for studying human developmental
processes, congenital diseases, and pathogen response mechanisms in addition to utility as …

Mucosal vaccines offer the potential to trigger robust protective immune responses at the
predominant sites of pathogen infection. In principle, the induction of adaptive immunity at …

Adenoviral vectors have been explored as vaccine agents for a range of infectious diseases,
and their ability to induce a potent and balanced immune response made them logical …

Background SARS-CoV-2 has caused millions of deaths, and, since Aug 11, 2020, 20
intramuscular COVID-19 vaccines have been approved for use. We aimed to evaluate the …

Vaccines represent the single most cost-efficient and equitable way to combat and eradicate
infectious diseases. While traditional licensed vaccines consist of either …

Background Intranasal vaccination may induce protective local and systemic immune
responses against respiratory pathogens. A number of intranasal SARS-CoV-2 vaccine …

Transmission-blocking strategies that slow the spread of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and protect against coronavirus disease 2019 (COVID-19) are …

There is an urgent need for effective countermeasures against the current emergence and
accelerating expansion of coronavirus disease 2019 (COVID-19), caused by severe acute …

The unprecedented coronavirus disease 2019 (COVID-19) epidemic has created a
worldwide public health emergency, and there is an urgent need to develop an effective …

Most of what we know about adaptive immunity has come from inbred mouse studies, using
methods that are often difficult or impossible to confirm in humans. In addition, vaccine …