Cancer vaccine therapeutics: limitations and effectiveness—A literature review
M Kaczmarek, J Poznańska, F Fechner, N Michalska… - Cells, 2023 - mdpi.com
In recent years, there has been a surge of interest in tumor microenvironment-associated
cancer vaccine therapies. These innovative treatments aim to activate and enhance the …
cancer vaccine therapies. These innovative treatments aim to activate and enhance the …
Mechanisms and challenges of nanocarriers as non-viral vectors of therapeutic genes for enhanced pulmonary delivery
H Wang, L Qin, X Zhang, J Guan, S Mao - Journal of Controlled Release, 2022 - Elsevier
With the rapid development of biopharmaceuticals and the outbreak of COVID-19, the world
has ushered in a frenzy to develop gene therapy. Therefore, therapeutic genes have …
has ushered in a frenzy to develop gene therapy. Therefore, therapeutic genes have …
CRISPR/Cas9 genome editing for tissue‐specific in vivo targeting: nanomaterials and translational perspective
Clustered randomly interspaced short palindromic repeats (CRISPRs) and its associated
endonuclease protein, ie, Cas9, have been discovered as an immune system in bacteria …
endonuclease protein, ie, Cas9, have been discovered as an immune system in bacteria …
Electrostatic Attractive Self‐Delivery of siRNA and Light‐Induced Self‐Escape for Synergistic Gene Therapy
Y Yang, H Ning, T Xia, J Du, W Sun, J Fan… - Advanced …, 2023 - Wiley Online Library
Small interfering RNA (siRNA) holds immense promise for suppressing gene expression
and treating various life‐threatening diseases, including cancer. However, efficient delivery …
and treating various life‐threatening diseases, including cancer. However, efficient delivery …
Recent advances in nanotechnology approaches for non-viral gene therapy
Gene therapy has shown great potential in the treatment of many diseases by
downregulating the expression of certain genes. The development of gene vectors as a …
downregulating the expression of certain genes. The development of gene vectors as a …
Chitosan in oral drug delivery formulations: A review
Nanoformulations have become increasingly useful as drug delivery technologies in recent
decades. As therapeutics, oral administration is the most common delivery method, although …
decades. As therapeutics, oral administration is the most common delivery method, although …
New advances in biomedical application of polymeric micelles
A Figueiras, C Domingues, I Jarak, AI Santos, A Parra… - Pharmaceutics, 2022 - mdpi.com
In the last decade, nanomedicine has arisen as an emergent area of medicine, which
studies nanometric systems, namely polymeric micelles (PMs), that increase the solubility …
studies nanometric systems, namely polymeric micelles (PMs), that increase the solubility …
Polymeric nanoparticles—Tools in a drug delivery system in selected cancer therapies
M Madej, N Kurowska, B Strzalka-Mrozik - Applied Sciences, 2022 - mdpi.com
The increase in cancer cases is undoubtedly affecting the development of new therapeutic
approaches. Polymeric nanoparticles are of great interest. Due to their relatively small size …
approaches. Polymeric nanoparticles are of great interest. Due to their relatively small size …
De novo designed peptides for cellular delivery and subcellular localisation
Increasingly, it is possible to design peptide and protein assemblies de novo from first
principles or computationally. This approach provides new routes to functional synthetic …
principles or computationally. This approach provides new routes to functional synthetic …
Applications of ultrasound-mediated drug delivery and gene therapy
Gene therapy has continuously evolved throughout the years since its first proposal to
develop more specific and effective transfection, capable of treating a myriad of health …
develop more specific and effective transfection, capable of treating a myriad of health …