A comprehensive review of caged phosphines: synthesis, catalytic applications, and future perspectives
Phosphines have played an important role in the rapid rise of transition metal-catalysed
processes and with the possibility of fine-tuning the electronic and steric properties of these …
processes and with the possibility of fine-tuning the electronic and steric properties of these …
[HTML][HTML] Iridium-and palladium-based catalysts in the pharmaceutical industry
Transition metal catalysts play a vital role in a wide range of industrial organic processes.
The large-scale production of chemicals relying on catalyzed organic reactions represents a …
The large-scale production of chemicals relying on catalyzed organic reactions represents a …
Discovery of novel furo[2,3‐d]pyrimidin‐2‐one–1,3,4‐oxadiazole hybrid derivatives as dual antiviral and anticancer agents that induce apoptosis
A new series of furo [2, 3‐d] pyrimidine–1, 3, 4‐oxadiazole hybrid derivatives were
synthesized via an environmentally friendly, multistep synthetic tool and a one‐pot …
synthesized via an environmentally friendly, multistep synthetic tool and a one‐pot …
Cu(II)/PTABS-Promoted, Regioselective SNAr Amination of Polychlorinated Pyrimidines with Mechanistic Understanding
H Shet, KC Gunturu, SJ Gharpure… - The Journal of …, 2023 - ACS Publications
Regioselective amination of polyhalogenated heteroarenes (especially pyrimidines) has
extensive synthetic and commercial relevance for drug synthesis applications but is plagued …
extensive synthetic and commercial relevance for drug synthesis applications but is plagued …
[HTML][HTML] Scale-up of a Heck alkenylation reaction: Application to the synthesis of an amino-modifier nucleoside 'Ruth linker'
Ruth linker is a C5 pyrimidine modified nucleoside analogue widely utilized for the
incorporation of a primary amine in a synthetic oligonucleotide. The increasing demand for …
incorporation of a primary amine in a synthetic oligonucleotide. The increasing demand for …
Cu (II)/PTABS-Promoted, Chemoselective Amination of HaloPyrimidines
V Phulwale, H Shet, KC Gunturu, SR Rout… - The Journal of …, 2024 - ACS Publications
Chemoselective amination is a highly desired synthetic methodology, given its importance
as a possible strategy to synthesize various drug molecules and agrochemicals. We, herein …
as a possible strategy to synthesize various drug molecules and agrochemicals. We, herein …
Room‐Temperature Dialkylamination of Chloroheteroarenes Using a Cu (II)/PTABS Catalytic System
The dimethylamino functionality has significant importance in industrially relevant molecules
and methodologies to install these efficiently are highly desirable. We report herein a highly …
and methodologies to install these efficiently are highly desirable. We report herein a highly …
1, 3, 5‐Triaza‐7‐phosphaadamantane (PTA) Derived Caged Phosphines for Palladium‐Catalyzed Selective Functionalization of Nucleosides and Heteroarenes
SS Murthy Bandaru, S Bhilare, C Schulzke… - The Chemical …, 2021 - Wiley Online Library
Phosphines have, in combination with transition metals, played a pivotal role in the rapid
development of efficient catalytic processes. Caged phosphines constitute a class of three …
development of efficient catalytic processes. Caged phosphines constitute a class of three …
Water‐Soluble Pd‐Imidate Complexes as Versatile Catalysts for the Modification of Unprotected Halonucleosides
JL Serrano - The Chemical Record, 2022 - Wiley Online Library
Modification of unprotected nucleosides has been attracting continuous interest, since these
building blocks themselves and their phosphate‐upgraded corresponding nucleotides have …
building blocks themselves and their phosphate‐upgraded corresponding nucleotides have …
[HTML][HTML] Na2 [Pd (saccharinate) 4]: A new phosphine-free water-soluble catalyst with singular structure for modification of ribose nucleosides at room temperature
The easy synthesis of the anionic palladium catalyst containing saccharinate as only ligand
Na 2 [Pd (saccharinate) 4](I), starting from either Na 2 [PdCl 4] or Pd (AcO) 2, is reported …
Na 2 [Pd (saccharinate) 4](I), starting from either Na 2 [PdCl 4] or Pd (AcO) 2, is reported …