The principal role of prolactin in mammals is the regulation of lactation. Prolactin is a
hormone that is mainly synthesized and secreted by lactotroph cells in the anterior pituitary …

Context: Central hypothyroidism (CH) is a particular hypothyroid condition due to an
insufficient stimulation by TSH of an otherwise normal thyroid gland. This condition raises …

Objectives: Central hypothyroidism (CeH) is a rare form of hypothyroidism characterized by
insufficient thyroid stimulation due to disturbed pituitary and/or hypothalamic functioning …

The genetic basis for combined pituitary hormone deficiency (CPHD) is complex, involving
30 genes in a variety of syndromic and nonsyndromic presentations. Molecular diagnosis of …

The fast technological development, particularly single nucleotide polymorphism array, array-
comparative genomic hybridization, and whole exome sequencing, has led to the discovery …

Context: Genetics plays a major role in determining an individual's height. Although there
are many monogenic disorders that lead to perturbations in growth and result in short …

Central hypothyroidism is a rare and heterogeneous disorder that is characterized by a
defect in thyroid hormone secretion in an otherwise normal thyroid gland due to insufficient …

Context: Kallmann syndrome (KS), combined pituitary hormone deficiency (CPHD), and
septo-optic dysplasia (SOD) all result from development defects of the anterior midline in the …

Central hypothyrodism (CeH) is a hypothyroid state caused by an insufficient stimulation by
thyrotropin (TSH) of an otherwise normal thyroid gland. Several advancements, including …

The development of the anterior pituitary gland occurs in distinct sequential developmental
steps, leading to the formation of a complex organ containing five different cell types …