Advances in understanding cancer genomes through second-generation sequencing

M Meyerson, S Gabriel, G Getz - Nature Reviews Genetics, 2010 - nature.com
Cancers are caused by the accumulation of genomic alterations. Therefore, analyses of
cancer genome sequences and structures provide insights for understanding cancer …

[HTML][HTML] High-risk human papillomaviral oncogenes E6 and E7 target key cellular pathways to achieve oncogenesis

NSL Yeo-Teh, Y Ito, S Jha - International journal of molecular sciences, 2018 - mdpi.com
Infection with high-risk human papillomavirus (HPV) has been linked to several human
cancers, the most prominent of which is cervical cancer. The integration of the viral genome …

The Lower Anogenital Squamous Terminology Standardization project for HPV-associated lesions: background and consensus recommendations from the College of …

TM Darragh, TJ Colgan, JT Cox, DS Heller… - International Journal …, 2013 - journals.lww.com
The terminology for human papillomavirus (HPV)-associated squamous lesions of the lower
anogenital tract has a long history marked by disparate diagnostic terms derived from …

Why do viruses cause cancer? Highlights of the first century of human tumour virology

PS Moore, Y Chang - Nature reviews cancer, 2010 - nature.com
The year 2011 marks the centenary of Francis Peyton Rous's landmark experiments on an
avian cancer virus. Since then, seven human viruses have been found to cause 10–15% of …

[HTML][HTML] Papillomaviruses in the causation of human cancers—a brief historical account

H Zur Hausen - Virology, 2009 - Elsevier
Approximately 35 years ago a role of human papillomaviruses (HPV) in cervical cancer has
been postulated. Today it is well established that this very heterogeneous virus family …

[HTML][HTML] Papillomaviruses and cancer: from basic studies to clinical application

H Zur Hausen - Nature reviews cancer, 2002 - nature.com
Links between human papillomaviruses (HPVs) and cervical cancer were first suspected
almost 30 years ago. DNA of specific HPV types has since been found in almost all cervical …

Clonal integration of a polyomavirus in human Merkel cell carcinoma

H Feng, M Shuda, Y Chang, PS Moore - Science, 2008 - science.org
Merkel cell carcinoma (MCC) is a rare but aggressive human skin cancer that typically
affects elderly and immunosuppressed individuals, a feature suggestive of an infectious …

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

N Dyson, PM Howley, K Münger, ED Harlow - Science, 1989 - science.org
Deletions or mutations of the retinoblastoma gene, RB1, are common features of many
tumors and tumor cell lines. Recently, the RB1 gene product, p105-RB, has been shown to …

World Health Organization classification of tumours: Pathology & genetics of tumours of the urinary system and male genital organs

TY Chan - Urology, 2005 - goldjournal.net
This 2004 volume in the World Health Organization series on histologic and genetic typing
of human tumors covers tumors of the kidney, urinary system, prostate, testis and …

A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer

M Herfs, Y Yamamoto, A Laury… - Proceedings of the …, 2012 - National Acad Sciences
Infection by carcinogenic human papillomaviruses (HPV) results in precancers [cervical
intraepithelial neoplasia (CIN)] and cancers near the ectoendocervical squamocolumnar …