[HTML][HTML] Inhibiting mir-34a-5p regulates doxorubicin-induced autophagy disorder and alleviates myocardial pyroptosis by targeting Sirt3-AMPK pathway
Z Zhong, Y Gao, J Zhou, F Wang, P Zhang, S Hu… - Biomedicine & …, 2023 - Elsevier
Doxorubicin (DOX) is a commonly used chemotherapy drug widely applied in various
cancers such as breast cancer, leukemia, and sarcomas. However, its usage is limited by …
cancers such as breast cancer, leukemia, and sarcomas. However, its usage is limited by …
[HTML][HTML] Programmed death of cardiomyocytes in cardiovascular disease and new therapeutic approaches
K Cai, H Jiang, Y Zou, C Song, K Cao, S Chen… - Pharmacological …, 2024 - Elsevier
Cardiovascular diseases (CVDs) have a complex pathogenesis and pose a major threat to
human health. Cardiomyocytes have a low regenerative capacity, and their death is a key …
human health. Cardiomyocytes have a low regenerative capacity, and their death is a key …
DL-3-n-butylphthalide attenuates doxorubicin-induced acute cardiotoxicity via Nrf2/HO-1 signaling pathway
D Li, W Zhang, H Fu, X Wang, Y Tang, C Huang - Heliyon, 2024 - cell.com
Doxorubicin (DOX) is a widely used chemotherapeutic drug known to cause dose-
dependent myocardial toxicity, which limits its clinical potential. DL-3-n-butylphthalide …
dependent myocardial toxicity, which limits its clinical potential. DL-3-n-butylphthalide …
Galangin attenuates doxorubicin‐induced cardiotoxicity via activating nuclear factor erythroid 2‐related factor 2/heme oxygenase 1 signaling pathway to suppress …
G Fang, X Li, F Yang, T Huang, C Qiu… - Phytotherapy …, 2023 - Wiley Online Library
Doxorubicin (DOX) has aroused contradiction between its potent anti‐tumor capacity and
severe cardiotoxicity. Galangin (Gal) possesses antioxidant, anti‐inflammatory, and …
severe cardiotoxicity. Galangin (Gal) possesses antioxidant, anti‐inflammatory, and …
Aerobic exercise mitigates high-fat diet-induced cardiac dysfunction, pyroptosis, and inflammation by inhibiting STING-NLRP3 signaling pathway
Z Xu, Z Ma, X Zhao, B Zhang - Molecular and Cellular Biochemistry, 2024 - Springer
Obesity has been identified as an independent risk factor for cardiovascular disease. Recent
reports have highlighted the significance of stimulator of interferon genes (STING)-NOD-like …
reports have highlighted the significance of stimulator of interferon genes (STING)-NOD-like …
[PDF][PDF] The protective effects of traditional Chinese medicine ingredients against doxorubicin-induced cardiotoxicity
Z Wang, Q Wu - 2024 - tmrjournals.cn
Doxorubicin (DOX), also known as adriamycin, is an anthracycline chemotherapy drug that
exerts anticancer effects. However, the clinical application of DOX is severely limited by its …
exerts anticancer effects. However, the clinical application of DOX is severely limited by its …
Overexpression of miR-210 rescues human cardiomyocytes from doxorubicin-induced stress
J Guthormsen - 2024 - ntnuopen.ntnu.no
Bakgrunn: Fremskritt i tidlig diagnostikk og behandling av kreftsykdommer har ført til en
økning i antall pasienter som overlever kreft. Denne økningen har samtidig ført til at stadig …
økning i antall pasienter som overlever kreft. Denne økningen har samtidig ført til at stadig …