Role of human milk bioactives on infants' gut and immune health

LE Carr, MD Virmani, F Rosa, D Munblit… - Frontiers in …, 2021 - frontiersin.org
Exclusive human milk feeding of the newborn is recommended during the first 6 months of
life to promote optimal health outcomes during early life and beyond. Human milk contains a …

Bioactive peptides from food fermentation: A comprehensive review of their sources, bioactivities, applications, and future development

KF Chai, AYH Voo, WN Chen - Comprehensive Reviews in …, 2020 - Wiley Online Library
Bioactive peptides (BPs) are specific protein fragments that exert various beneficial effects
on human bodies and ultimately influence health, depending on their structural properties …

Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin

E Pretorius, M Vlok, C Venter, JA Bezuidenhout… - Cardiovascular …, 2021 - Springer
Background Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2)-induced
infection, the cause of coronavirus disease 2019 (COVID-19), is characterized by acute …

Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may also …

A Kruger, M Vlok, S Turner, C Venter… - Cardiovascular …, 2022 - Springer
Background Post-acute sequelae of COVID-19 (PASC), also now known as long COVID,
has become a major global health and economic burden. Previously, we provided evidence …

The in vitro antiviral activity of lactoferrin against common human coronaviruses and SARS-CoV-2 is mediated by targeting the heparan sulfate co-receptor

Y Hu, X Meng, F Zhang, Y Xiang… - Emerging microbes & …, 2021 - Taylor & Francis
ABSTRACT Coronavirus disease 2019 (COVID-19) is an ongoing pandemic that lacks
effective therapeutic interventions. SARS-CoV-2 infects ACE2-expressing cells and gains …

[HTML][HTML] The role of iron in the pathogenesis of COVID-19 and possible treatment with lactoferrin and other iron chelators

HM Habib, S Ibrahim, A Zaim, WH Ibrahim - Biomedicine & …, 2021 - Elsevier
Iron overload is increasingly implicated as a contributor to the pathogenesis of COVID-19.
Indeed, several of the manifestations of COVID-19, such as inflammation, hypercoagulation …

The Role of Streptococcus spp. in Bovine Mastitis

T Kabelitz, E Aubry, K van Vorst, T Amon, M Fulde - Microorganisms, 2021 - mdpi.com
The Streptococcus genus belongs to one of the major pathogen groups inducing bovine
mastitis. In the dairy industry, mastitis is the most common and costly disease. It not only …

Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19

C Mirabelli, JW Wotring, CJ Zhang… - Proceedings of the …, 2021 - National Acad Sciences
The global spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
and the associated disease COVID-19, requires therapeutic interventions that can be rapidly …

A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications

DB Kell, GJ Laubscher, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Post-acute sequelae of COVID (PASC), usually referred to as 'Long COVID'(a phenotype of
COVID-19), is a relatively frequent consequence of SARS-CoV-2 infection, in which …

The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …

DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …