[HTML][HTML] Nanoparticle surface functionalization: how to improve biocompatibility and cellular internalization

G Sanità, B Carrese, A Lamberti - Frontiers in molecular biosciences, 2020 - frontiersin.org
The use of nanoparticles (NP) in diagnosis and treatment of many human diseases,
including cancer, is of increasing interest. However, cytotoxic effects of NPs on cells and the …

Diatoms with invaluable applications in nanotechnology, biotechnology, and biomedicine: recent advances

N Rabiee, M Khatami, G Jamalipour Soufi… - ACS biomaterials …, 2021 - ACS Publications
Diatoms are unicellular microalga found in soil and almost every aquatic environment
(marine and fresh water). Biogenic silica and diatoms are attractive for biotechnological and …

[HTML][HTML] Effects of morphology and size of nanoscale drug carriers on cellular uptake and internalization process: a review

W Zhang, R Taheri-Ledari, F Ganjali… - RSC …, 2023 - pubs.rsc.org
In the field of targeted drug delivery, the effects of size and morphology of drug nanocarriers
are of great importance and need to be discussed in depth. To be concise, among all the …

SERS quantification of galunisertib delivery in colorectal cancer cells by plasmonicassisted diatomite nanoparticles

S Managò, C Tramontano, D Delle Cave, G Chianese… - Small, 2021 - Wiley Online Library
The small molecule Galunisertib (LY2157299, LY) shows multiple anticancer activities
blocking the transforming growth factor螃1 receptor, responsible for the epithelialto …

Surface-enhanced Raman and fluorescence spectroscopy with an all-dielectric metasurface

S Romano, G Zito, S Managò, G Calafiore… - The Journal of …, 2018 - ACS Publications
Plasmonic substrates play a crucial role in the confinement and manipulation of localized
electromagnetic fields at the nanoscale. The large electromagnetic field enhancement at …

[HTML][HTML] Natural diatom biosilica as microshuttles in drug delivery systems

J Delasoie, F Zobi - Pharmaceutics, 2019 - mdpi.com
Unicellular diatom microalgae are a promising natural resource of porous biosilica. These
microorganisms produce around their membrane a highly porous and extremely structured …

[HTML][HTML] Diatoms green nanotechnology for biosilica-based drug delivery systems

M Terracciano, L De Stefano, I Rea - Pharmaceutics, 2018 - mdpi.com
Diatom microalgae are the most outstanding natural source of porous silica. The diatom cell
is enclosed in a three-dimensional (3-D) ordered nanopatterned silica cell wall, called …

[HTML][HTML] Nanostructured biosilica of diatoms: From water world to biomedical applications

C Tramontano, G Chianese, M Terracciano… - Applied Sciences, 2020 - mdpi.com
Diatoms—unicellular photosynthetic algae—are promising natural sources of
nanostructured silica. These microorganisms produce in their membrane approximately a …

[HTML][HTML] Biomimetic diatom biosilica and its potential for biomedical applications and prospects: a review

KH Min, DH Kim, S Youn, SP Pack - International Journal of Molecular …, 2024 - mdpi.com
Diatom biosilica is an important natural source of porous silica, with three-dimensional
ordered and nanopatterned structures referred to as frustules. The unique features of diatom …

Green synthesis of silica and silicon nanoparticles and their biomedical and catalytic applications

N Shafiei, M Nasrollahzadeh… - Comments on Inorganic …, 2021 - Taylor & Francis
Silica and silicon nanomaterials have diverse applications in the field of drug/gene delivery,
lightweight aggregates, regenerative medicine, tissue engineering, cancer …