Role of endocrine-disrupting chemicals in the pathogenesis of non-alcoholic fatty liver disease: a comprehensive review
Non-alcoholic fatty liver disease (NAFLD) is considered the most common liver disorder,
affecting around 25% of the population worldwide. It is a complex disease spectrum, closely …
affecting around 25% of the population worldwide. It is a complex disease spectrum, closely …
Metabolism-disrupting chemicals affecting the liver: screening, testing, and molecular pathway identification
K Fritsche, A Ziková-Kloas, P Marx-Stoelting… - International Journal of …, 2023 - mdpi.com
The liver is the central metabolic organ of the body. The plethora of anabolic and catabolic
pathways in the liver is tightly regulated by physiological signaling but may become …
pathways in the liver is tightly regulated by physiological signaling but may become …
Disruptive effects of nonylphenol on reproductive hormones, antioxidant enzymes, and histology of liver, kidney and gonads in Caspian trout smolts
The endocrine-disrupting effect of pollutants such as alkylphenols has been considered a
major concern during recent years. Although the effects of nonylphenol on the reproductive …
major concern during recent years. Although the effects of nonylphenol on the reproductive …
Chronic exposure to nonylphenol induces oxidative stress and liver damage in male zebrafish (Danio rerio): Mechanistic insight into cellular energy sensors, lipid …
U Mukherjee, A Samanta, S Biswas, S Ghosh… - Chemico-Biological …, 2022 - Elsevier
Nonylphenol (NP), an environmentally persistent and toxic endocrine-disrupting chemical
with estrogenic properties, has severe implications on humans and wildlife. Accumulating …
with estrogenic properties, has severe implications on humans and wildlife. Accumulating …
Steatosis induced by nonylphenol in HepG2 cells and the intervention effect of curcumin
D Shan, J Wang, Q Di, Q Jiang, Q Xu - Food & Function, 2022 - pubs.rsc.org
Non-alcoholic fatty liver disease (NAFLD) has increasingly become a serious public health
problem. There is growing evidence that nonylphenol (NP) exposure may cause steatosis …
problem. There is growing evidence that nonylphenol (NP) exposure may cause steatosis …
Palliative effects of zinc sulfate against the immunosuppressive, hepato-and nephrotoxic impacts of nonylphenol in Nile tilapia (Oreochromis niloticus)
WAM Mohamed, W El-Houseiny, RE Ibrahim… - Aquaculture, 2019 - Elsevier
Nonylphenol (NP) is a widespread contaminant in the ecosystem. Zinc is an essential trace
element with many physiological activities. The existing study aimed to examine the possible …
element with many physiological activities. The existing study aimed to examine the possible …
Estrogen deficiency aggravates fluoride-induced liver damage and lipid metabolism disorder in rats
Y Yu, B Zhou, Y Yang, CX Guo, J Zhao… - Biological Trace Element …, 2022 - Springer
Estrogen exerts essential role in liver metabolism, and its deficiency is frequently
accompanied by a series of metabolic disorder diseases. To investigate the role of estrogen …
accompanied by a series of metabolic disorder diseases. To investigate the role of estrogen …
Modulatory effects of green tea extract against the hepatotoxic effects of 4-nonylphenol in catfish (Clarias gariepinus)
AEDH Sayed, HAM Soliman - Ecotoxicology and environmental safety, 2018 - Elsevier
The antioxidant role of the green tea (Camellia sinensis) extract (GTE) was examined to
remedy the toxic effects of (0.2 mg l− 1) 4-nonylphenol (4-NP). Biochemical parameters …
remedy the toxic effects of (0.2 mg l− 1) 4-nonylphenol (4-NP). Biochemical parameters …
In vitro to in vivo extrapolation for predicting human equivalent dose of phenolic endocrine disrupting chemicals: PBTK model development, biological pathways …
R Xie, X Wang, Y Xu, L Zhang, M Ma, Z Wang - Science of The Total …, 2023 - Elsevier
In vitro to in vivo (IVIVE) leverages in vitro high-throughput biological responses to predict
the corresponding in vivo exposures and further estimate the human safe dose. However, for …
the corresponding in vivo exposures and further estimate the human safe dose. However, for …
The effect of nonylphenol exposure on the stimulation of melanomacrophage centers, estrogen and testosterone level, and ERα gene expression in goldfish
The present study tried to measure the formation of melanomacrophage centers (MMCs) in
various organs of male and female goldfish exposed to nonylphenol (NP) and aimed to …
various organs of male and female goldfish exposed to nonylphenol (NP) and aimed to …