[HTML][HTML] Exposome and unhealthy aging: environmental drivers from air pollution to occupational exposures

T Pandics, D Major, V Fazekas-Pongor, Z Szarvas… - Geroscience, 2023 - Springer
The aging population worldwide is facing a significant increase in age-related non-
communicable diseases, including cardiovascular and brain pathologies. This …

[HTML][HTML] State of knowledge on molecular adaptations to exercise in humans: historical perspectives and future directions

KM Lavin, PM Coen, LC Baptista, MB Bell… - Comprehensive …, 2022 - ncbi.nlm.nih.gov
For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …

Diabetes mellitus and Parkinson's disease: a systematic review and meta-analyses

K Komici, GD Femminella… - Journal of …, 2021 - content.iospress.com
Background: A link between diabetes mellitus (DM) and Parkinson's disease (PD) have
been proposed but evidence are sparse and inconsistent. Objective: Perform a systematic …

Type-2 diabetes and risk of dementia: observational and Mendelian randomisation studies in 1 million individuals

JQ Thomassen, JS Tolstrup, M Benn… - Epidemiology and …, 2020 - cambridge.org
AimsIn observational studies, type-2 diabetes is associated with increased risk of dementia;
however, the causal nature of this association remains unanswered. In an unselected …

[HTML][HTML] Interaction between Alzheimer's disease and cerebral small vessel disease: a review focused on neuroimaging markers

SE Kim, HJ Kim, H Jang, MW Weiner… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is characterized by the presence of β-amyloid (Aβ) and tau, and
subcortical vascular cognitive impairment (SVCI) is characterized by cerebral small vessel …

Increases in hypertension-induced cerebral microhemorrhages exacerbate gait dysfunction in a mouse model of Alzheimer's disease

Á Nyúl-Tóth, S Tarantini, T Kiss, P Toth, V Galvan… - Geroscience, 2020 - Springer
Clinical studies show that cerebral amyloid angiopathy (CAA) associated with Alzheimer's
disease (AD) and arterial hypertension are independent risk factors for cerebral …

Cognitive impairment in patients with stroke

CE D'Souza, MRF Greenway… - Seminars in …, 2021 - thieme-connect.com
Despite substantial advances in stroke care, vascular cognitive impairment remains a
prominent source of disability. Unlike sensorimotor impairments, cognition often continues to …

Age‐stratified longitudinal study of Alzheimer's and vascular dementia patients

IF Jørgensen, A Aguayo‐Orozco… - Alzheimer's & …, 2020 - Wiley Online Library
Introduction Similar symptoms, comorbidities and suboptimal diagnostic tests make the
distinction between different types of dementia difficult, although this is essential for …

[HTML][HTML] A unidirectional mapping of ICD-8 to ICD-10 codes, for harmonized longitudinal analysis of diseases

MK Pedersen, R Eriksson, R Reguant, C Collin… - European Journal of …, 2023 - Springer
Periodic revisions of the international classification of diseases (ICD) ensure that the
classification reflects new practices and knowledge; however, this complicates retrospective …

[HTML][HTML] Transcriptomic and network analysis highlight the association of diabetes at different stages of Alzheimer's disease

JA Santiago, V Bottero, JA Potashkin - Frontiers in Neuroscience, 2019 - frontiersin.org
Alzheimer's disease (AD) and type 2 diabetes (T2D) are among the most prevalent chronic
diseases affecting the aging population. Extensive research evidence indicates that T2D is a …