EBV primary infection in childhood and its relation to B‐cell lymphoma development: a mini‐review from a developing region

PA Chabay, MV Preciado - International journal of cancer, 2013 - Wiley Online Library
In most underdeveloped countries, the initial contact with Epstein Barr virus (EBV) usually
happens in the first decade of life and results in an asymptomatic infection, whereas in …

[HTML][HTML] Lymphotropic viruses EBV, KSHV and HTLV in Latin America: epidemiology and associated malignancies. a literature-based study by the RIAL-CYTED

P Chabay, D Lens, R Hassan, SM Rodríguez Pinilla… - Cancers, 2020 - mdpi.com
The Epstein–Barr virus (EBV), Kaposi sarcoma herpesvirus (KSHV) and human T-
lymphotropic virus (HTLV-1) are lymphomagenic viruses with region-specific induced …

Tumor-associated macrophages in pediatric classical Hodgkin lymphoma: association with Epstein-Barr virus, lymphocyte subsets, and prognostic impact

MHM Barros, R Hassan, G Niedobitek - Clinical cancer research, 2012 - AACR
Purpose: Tumor-infiltrating macrophages are associated with adverse outcome in adult
classical Hodgkin lymphoma (cHL). We have previously shown age-related changes in the …

[HTML][HTML] Macrophage polarization reflects T cell composition of tumor microenvironment in pediatric classical Hodgkin lymphoma and has impact on survival

MHM Barros, P Segges, G Vera-Lozada, R Hassan… - PloS one, 2015 - journals.plos.org
Macrophages have been implicated in the pathogenesis of classical Hodgkin lymphoma
(cHL) and have been suggested to have a negative impact on outcome. Most studies …

[HTML][HTML] Revisiting the tissue microenvironment of infectious mononucleosis: identification of EBV infection in T cells and deep characterization of immune profiles

MHM Barros, G Vera-Lozada, P Segges… - Frontiers in …, 2019 - frontiersin.org
To aid understanding of primary EBV infection, we have performed an in depth analysis of
EBV-infected cells and of local immune cells in tonsils from infectious mononucleosis (IM) …

Prevalence and prognostic significance of Epstein–Barr virus infection in classical Hodgkin's lymphoma: a meta-analysis

JH Lee, Y Kim, JW Choi, YS Kim - Archives of Medical Research, 2014 - Elsevier
Background and Aims The prevalence and prognostic significance of Epstein-Barr virus
(EBV) infection in classical Hodgkin's lymphomas (cHLs) remain elusive. To examine the …

Tumor microenvironment composition in pediatric classical Hodgkin lymphoma is modulated by age and Epstein‐Barr virus infection

MHM Barros, G Vera‐Lozada… - … journal of cancer, 2012 - Wiley Online Library
Classical Hodgkin lymphoma (cHL) is characterized by a small number of neoplastic cells in
a background of reactive cells. Children and adults differ in constitution and functionality of …

[HTML][HTML] Hodgkin lymphoma in childhood: clinicopathological features and therapy outcome at 2 centers from a developing country

LM Sherief, UR Elsafy, ER Abdelkhalek, NM Kamal… - Medicine, 2015 - journals.lww.com
Hodgkin lymphoma (HL) accounts for 5% to 6% of all childhood cancer. It displays
characteristic epidemiological, clinical, and pathological features according to various …

[HTML][HTML] Comparison of three methods for the detection of Epstein-Barr virus in Hodgkin's lymphoma in paraffin-embedded tissues

ZL Qi, XQ Han, J Hu, GH Wang… - Molecular …, 2013 - spandidos-publications.com
The percentage rate of Epstein-Barr virus (EBV)-positive cases of Hodgkin's lymphoma (HL)
ranges between 20 and 70% in various studies worldwide. To further explore the definite …

[HTML][HTML] Unique synapomorphies and high diversity in South American Raji-related Epstein-Barr virus genomes

P Alves, V Emmel, G Stefanoff, F Krsticevic… - Memórias do Instituto …, 2023 - SciELO Brasil
BACKGROUND Epstein-Barr virus (EBV) is a human gammaherpesvirus etiologically linked
to several benign and malignant diseases. EBV-associated malignancies exhibit an unusual …