[HTML][HTML] Carbapenem-Resistant Klebsiella pneumoniae: Virulence Factors, Molecular Epidemiology and Latest Updates in Treatment Options

T Karampatakis, K Tsergouli, P Behzadi - Antibiotics, 2023 - mdpi.com
Klebsiella pneumoniae is a Gram-negative opportunistic pathogen responsible for a variety
of community and hospital infections. Infections caused by carbapenem-resistant K …

[HTML][HTML] Klebsiella species: Taxonomy, hypervirulence and multidrug resistance

N Dong, X Yang, EWC Chan, R Zhang, S Chen - EBioMedicine, 2022 - thelancet.com
Members of the genus Klebsiella have rapidly evolved within the past decade, generating
organisms that simultaneously exhibit both multidrug resistance and hypervirulence (MDR …

[HTML][HTML] A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex

MMC Lam, RR Wick, SC Watts, LT Cerdeira… - Nature …, 2021 - nature.com
Klebsiella pneumoniae is a leading cause of antimicrobial-resistant (AMR) healthcare-
associated infections, neonatal sepsis and community-acquired liver abscess, and is …

[HTML][HTML] Genomic dissection of Klebsiella pneumoniae infections in hospital patients reveals insights into an opportunistic pathogen

CL Gorrie, M Mirčeta, RR Wick, LM Judd… - Nature …, 2022 - nature.com
Klebsiella pneumoniae is a major cause of opportunistic healthcare-associated infections,
which are increasingly complicated by the presence of extended-spectrum beta-lactamases …

[HTML][HTML] Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort

Y Qin, AS Havulinna, Y Liu, P Jousilahti, SC Ritchie… - Nature Genetics, 2022 - nature.com
Human genetic variation affects the gut microbiota through a complex combination of
environmental and host factors. Here we characterize genetic variations associated with …

[HTML][HTML] Virulence factors in hypervirulent Klebsiella pneumoniae

J Zhu, T Wang, L Chen, H Du - Frontiers in microbiology, 2021 - frontiersin.org
Hypervirulent Klebsiella pneumoniae (hvKP) has spread globally since first described in the
Asian Pacific Rim. It is an invasive variant that differs from the classical K. pneumoniae …

[HTML][HTML] A global perspective on the convergence of hypervirulence and carbapenem resistance in Klebsiella pneumoniae

P Lan, Y Jiang, J Zhou, Y Yu - Journal of global antimicrobial resistance, 2021 - Elsevier
Hypervirulence and carbapenem resistance have emerged as two distinct evolutionary
directions for Klebsiella pneumoniae, which pose a great threat in clinical settings. Multiple …

[HTML][HTML] Faecal microbiome-based machine learning for multi-class disease diagnosis

Q Su, Q Liu, RI Lau, J Zhang, Z Xu, YK Yeoh… - Nature …, 2022 - nature.com
Systemic characterisation of the human faecal microbiome provides the opportunity to
develop non-invasive approaches in the diagnosis of a major human disease. However …

Emerging antimicrobial-resistant high-risk Klebsiella pneumoniae clones ST307 and ST147

G Peirano, L Chen, BN Kreiswirth… - Antimicrobial agents and …, 2020 - Am Soc Microbiol
There is an enormous global public health burden due to antimicrobial-resistant (AMR)
Klebsiella pneumoniae high-risk clones. K. pneumoniae ST307 and ST147 are recent …

[HTML][HTML] A large-scale genomic snapshot of Klebsiella spp. isolates in Northern Italy reveals limited transmission between clinical and non-clinical settings

HA Thorpe, R Booton, T Kallonen, MJ Gibbon… - Nature …, 2022 - nature.com
The Klebsiella group, found in humans, livestock, plants, soil, water and wild animals, is
genetically and ecologically diverse. Many species are opportunistic pathogens and can …