An acute myocardial infarction, particularly one that is large and transmural, can produce
alterations in the topography of both the infarcted and noninfarcted regions of the ventricle …

To determine whether acute left ventricular failure associated with myocardial infarction
leads to architectural changes in the spared nonischemic portion of the ventricular wall …

Background Experimental evidence suggests that cyclosporine, which inhibits the opening
of mitochondrial permeability-transition pores, attenuates lethal myocardial injury that occurs …

Background—In animal models, brief periods of ischemia performed just at the time of
reperfusion can reduce infarct size, a phenomenon called postconditioning. In this …

BACKGROUND Left ventricular enlargement and the development of chronic heart failure
are potent predictors of survival in patients after myocardial infarction. Prospective studies …

Dilatation of infarcted segments (infarct expansion) may occur during recovery from
myocardial infarction, but the fate of noninfarcted segments is uncertain. Accordingly, left …

Background—We previously demonstrated that ischemic postconditioning decreases
creatine kinase release, a surrogate marker for infarct size, in patients with acute myocardial …

Objectives: This study aimed to determine whether post-conditioning at the time of
percutaneous coronary intervention could reduce reperfusion-induced myocardial edema in …

To determine whether the hypertrophic response of the surviving myocardium after infarction
leads to normalization of ventricular hemodynamics and wall stress, the left coronary artery …

Local ischemic postconditioning (IPost) and remote ischemic perconditioning (RIPer) are
promising cardioprotective therapies in ST-elevation myocardial infarction (STEMI). We …