Background Any form of screening aims to reduce disease‐specific and overall mortality,
and to improve a person's future quality of life. Screening for prostate cancer has generated …

Summary In 2010, the International Society of Geriatric Oncology (SIOG) developed
treatment guidelines for men with prostate cancer who are older than 70 years old. In 2013 …

OBJECTIVE. The purpose of this diagnostic meta-analysis was to determine the diagnostic
accuracy of multiparametric MRI for prostate cancer detection using anatomic T2-weighted …

OBJECTIVE To evaluate the efficacy and safety of degarelix, a new gonadotrophin‐
releasing hormone (GnRH) antagonist (blocker), vs leuprolide for achieving and maintaining …

Introduction Longitudinal studies have demonstrated that male hypogonadism could be
considered a surrogate marker of incident cardiovascular disease. Aim To evaluate the …

Introduction: This article, derived from a Technical Brief prepared for the Agency for
Healthcare Research and Quality, presents an overview on current models of care for …

Transrectal ultrasound (TRUS) was first developed in the 1970s. TRUS-guided biopsy,
under local anaesthetic and prophylactic antibiotics, is now the most widely accepted …

The use of MRI in prostate cancer management is controversial and current guidelines
underplay its role. Technological advances over the past 5 years, however, demand a re …

CONTEXT: Although magnetic resonance imaging (MRI) is emerging as the most commonly
used imaging modality for prostate cancer (PCa) detection, treatment planning, and follow …

Significant progress has been made in the understanding of the underlying cancer biology
of castration‐resistant prostate cancer (CRPC) with the androgen receptor (AR) signalling …