Pathogenesis of endometriosis: the origin of pain and subfertility

TM Gruber, S Mechsner - Cells, 2021 - mdpi.com
Endometriosis (EM) and adenomyosis (AM) are common conditions with pain and infertility
as the principal symptoms. The pathophysiology of pain in EM and AM comprises sensory …

Understanding psychological symptoms of endometriosis from a research domain criteria perspective

K van Stein, K Schubert, B Ditzen, C Weise - Journal of Clinical Medicine, 2023 - mdpi.com
Endometriosis is currently the second most common gynecological disease and is
associated with severe pain, vegetative impairment, and infertility. In association, there are …

Targeting YAP1 ameliorates progesterone resistance in endometriosis

SC Lin, WN Li, SC Lin, HT Hou, YC Tsai… - Human …, 2023 - academic.oup.com
Abstract STUDY QUESTION Does YAP1 inhibition alleviate progesterone resistance in
endometriosis? SUMMARY ANSWER YAP1 inhibition reduces progesterone resistance in …

Efficacy of N-acetylcysteine on endometriosis-related pain, size reduction of ovarian endometriomas, and fertility outcomes

E Anastasi, S Scaramuzzino, MF Viscardi… - International Journal of …, 2023 - mdpi.com
Background: Endometriosis is a chronic, estrogen-dependent, inflammatory disease, whose
pivotal symptoms are dysmenorrhea, dyspareunia, and chronic pelvic pain (CPP). Besides …

Progestins in the symptomatic management of endometriosis: a meta-analysis on their effectiveness and safety

JB Mitchell, S Chetty, F Kathrada - BMC Women's Health, 2022 - Springer
Background Endometriosis is a complex chronic disease that affects approximately 10% of
women of reproductive age worldwide and commonly presents with pelvic pain and …

[PDF][PDF] Unopposed estrogens: current and future perspectives.

MM Oliva, R Gambioli, G Forte, G Porcaro… - European Review for …, 2022 - researchgate.net
Estrogens and progestogens act on female reproductive tissues in opposite ways. As they
counteract each other actions, the correct balance between these two classes of hormones …

[HTML][HTML] Recurrence, reoperation, pregnancy rates, and risk factors for recurrence after ovarian endometrioma surgery: long-term follow-up of 756 women

SH Choi, S Kim, SW Lee, S Won, SH Shim… - Yonsei Medical …, 2023 - ncbi.nlm.nih.gov
Purpose The aims of this study were to evaluate the cumulative recurrence, reoperation, and
pregnancy rates after ovarian endometrioma surgery at a single institution for more than a 5 …

Treatment of endometriosis with dienogest in combination with traditional Chinese medicine: A systematic review and meta-analysis

Y Wu, Y Liu, H Jia, C Luo, H Chen - Frontiers in Surgery, 2022 - frontiersin.org
Background Endometriosis is now considered to be a systemic disease rather than a
disease that primarily affects the pelvis. Dienogest (DNG) has unique advantages in the …

Effects of breastfeeding on endometriosis-related pain: a prospective observational study

R Prosperi Porta, C Sangiuliano, A Cavalli… - International Journal of …, 2021 - mdpi.com
Endometriosis is a gynecological estrogen-dependent disease whose commonest pain
symptoms are dysmenorrhea, dyspareunia, and acyclic chronic pelvic pain (CPP). Hormonal …

The effect of surgery or medication on pain and quality of life in women with endometrioma. A systematic review and meta-analysis

A Keukens, V Veth, M Regis, V Mijatovic… - European Journal of …, 2023 - Elsevier
For patients with endometrioma it is unclear what treatment: surgery and/or medication, is
more effective in reducing pain and improving quality of life (QoL). This systematic review …