An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment

S Drożdżal, J Rosik, K Lechowicz, F Machaj… - Drug Resistance …, 2021 - Elsevier
The COVID-19 pandemic is one of the greatest threats to human health in the 21st century
with more than 257 million cases and over 5.17 million deaths reported worldwide (as of …

Ivermectin for preventing and treating COVID‐19

M Popp, M Stegemann, MI Metzendorf… - Cochrane Database …, 2021 - cochranelibrary.com
Background Ivermectin, an antiparasitic agent used to treat parasitic infestations, inhibits the
replication of viruses in vitro. The molecular hypothesis of ivermectin's antiviral mode of …

[PDF][PDF] Therapeutics and COVID-19: living guideline, 13 January 2023

World Health Organization - 2023 - apps.who.int
As of December 2022, there have been over 642 million confirmed cases of COVID-19 (10).
The pandemic has thus far claimed approximately 6.62 million lives (10). Vaccination is …

Efficacy of antiviral therapies for COVID-19: a systematic review of randomized controlled trials

CTR Vegivinti, KW Evanson, H Lyons, I Akosman… - BMC Infectious …, 2022 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) continues to pose a significant
threat to public health worldwide. The purpose of this study was to review current evidence …

[HTML][HTML] Ivermectin for prevention and treatment of COVID-19 infection: a systematic review, meta-analysis, and trial sequential analysis to inform clinical guidelines

A Bryant, TA Lawrie, T Dowswell… - American journal of …, 2021 - journals.lww.com
Ivermectin for Prevention and Treatment of COVID-19 Infectio... : American Journal of
Therapeutics Ivermectin for Prevention and Treatment of COVID-19 Infection: A Systematic …

Ivermectin as a potential treatment for mild to moderate COVID-19–a double blind randomized placebo-controlled trial

Ravikirti, R Roy, C Pattadar, R Raj, N Agarwal… - MedRxiv, 2021 - medrxiv.org
Objective Ivermectin has been suggested as a treatment for COVID-19. This randomised
control trial was conducted to test the efficacy of Ivermectin in the treatment of mild and …

The effects of hyperbaric oxygen therapy (HBOT) on coronavirus disease-2019 (COVID-19): a systematic review

S Oliaei, SA SeyedAlinaghi, M Mehrtak… - European journal of …, 2021 - Springer
Background Oxygenation serves as a cornerstone in the treatment of COVID-19, and several
methods have been extensively studied so far. Herein, we aimed to systematically review …

Drug-induced liver injury in COVID-19 patients: a systematic review

F Sodeifian, ZS Seyedalhosseini, N Kian… - Frontiers in …, 2021 - frontiersin.org
Introduction: The severity of COVID-19 may be correlated with the risk of liver injury
development. An increasing number of studies indicate that degrees of hepatotoxicity has …

[PDF][PDF] Retracted: meta-analysis of randomized trials of ivermectin to treat SARS-CoV-2 infection

A Hill, A Garratt, J Levi, J Falconer, L Ellis… - Open Forum …, 2021 - academic.oup.com
Ivermectin is an antiparasitic drug being investigated for repurposing against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Ivermectin showed in vitro activity …

Ivermectin and outcomes from Covid‐19 pneumonia: a systematic review and meta‐analysis of randomized clinical trial studies

TI Hariyanto, DA Halim, J Rosalind… - Reviews in medical …, 2022 - Wiley Online Library
Ivermectin is an FDA‐approved drug for a parasitic disease that has broad antiviral activity.
This study aims to analyse the efficacy of ivermectin in improving the Covid‐19 outcomes …