[HTML][HTML] Mechanisms of action of ozone therapy in emerging viral diseases: immunomodulatory effects and therapeutic advantages with reference to SARS-CoV-2

A Cenci, I Macchia, V La Sorsa, C Sbarigia… - Frontiers in …, 2022 - frontiersin.org
Medical oxygen-ozone (O2-O3) is a successful therapeutic approach accounting on the
assessed beneficial action of ozone in the range 30–45 μg/ml (expanded range 10–80 …

[HTML][HTML] The Mito-Hormetic mechanisms of ozone in the clearance of SARS-CoV2 and in the COVID-19 therapy

S Chirumbolo, A Varesi, M Franzini, L Valdenassi… - Biomedicines, 2022 - mdpi.com
An increasing body of evidence in the literature is reporting the feasibility of using medical
ozone as a possible alternative and adjuvant treatment for COVID-19 patients, significantly …

[HTML][HTML] Differential co-expression network analysis reveals key hub-high traffic genes as potential therapeutic targets for COVID-19 pandemic

A Hasankhani, A Bahrami, N Sheybani, B Aria… - Frontiers in …, 2021 - frontiersin.org
Background The recent emergence of COVID-19, rapid worldwide spread, and incomplete
knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited …

[PDF][PDF] Fatigue in post-acute sequelae of SARS-CoV2 (PASC) treated with oxygen-ozone autohemotherapy-preliminary results on 100 patients

U Tirelli, M Franzini, L Valdenassi… - Eur Rev Med …, 2021 - backoffice.ossigenoozono.it
OBJECTIVE: Post-acute sequelae of SARS-CoV2 infection (PASC) are a novel terminology
used to describe post-COVID persistent symptoms, mimicking somehow the previously …

[HTML][HTML] The biological activity of medical ozone in the hormetic range and the role of full expertise professionals

M Franzini, L Valdenassi, S Pandolfi, U Tirelli… - Frontiers in Public …, 2022 - frontiersin.org
The recent paper by Cenci et al.(1) provided us with an overview of the biological action of
medical ozone (O3) on infectious agents, with a particular focus on its antiviral activity …

[HTML][HTML] Insights on the role of l-lactate as a signaling molecule in skin aging

S Chirumbolo, D Bertossi, P Magistretti - Biogerontology, 2023 - Springer
Abstract l-lactate is a catabolite from the anaerobic metabolism of glucose, which plays a
paramount role as a signaling molecule in various steps of the cell survival. Its activity, as a …

Fluorescent probes for ozone-specific recognition: An historical overview and future perspectives

D Zheng, J Huang, Y Fang, Y Deng, C Peng… - Trends in Environmental …, 2023 - Elsevier
Ozone (O 3) is not only an environment pollutant at tropospheric or ground-level that poses
a potential threat to human health, but it also belongs to the class of reactive oxygen species …

[HTML][HTML] The Oxygen–Ozone Adjunct Medical Treatment According to the Protocols from the Italian Scientific Society of Oxygen–Ozone Therapy: How Ozone …

S Chirumbolo, L Valdenassi, U Tirelli, G Ricevuti… - Biology, 2023 - mdpi.com
Simple Summary In this article, we show the effect of ozonated blood, ie, ozone used via
major autohemotherapy, on fighting antibiotic resistance in post-surgical infected wounds …

Ozone as an adjuvant therapy for COVID-19: A systematic review and meta-analysis

DS Budi, IF Rofananda, NR Pratama, H Sutanto… - International …, 2022 - Elsevier
Objective Ozone adjuvant in COVID-19 management showed conflicting results in prior
studies. Here, we aimed to comprehensively evaluate benefits and side effects of ozone as …

[HTML][HTML] The hidden pandemic of COVID-19-induced organizing pneumonia

E Bazdyrev, M Panova, V Zherebtsova, A Burdenkova… - Pharmaceuticals, 2022 - mdpi.com
Since the beginning of the COVID-19 pandemic, clinical, radiological, and histopathological
studies have provided evidence that organizing pneumonia is a possible consequence of …