An introduction to markers, quantitative trait loci (QTL) mapping and marker-assisted selection for crop improvement: the basic concepts

BCY Collard, MZZ Jahufer, JB Brouwer, ECK Pang - Euphytica, 2005 - Springer
Recognizing the enormous potential of DNA markers in plant breeding, many agricultural
research centers and plant breeding institutes have adopted the capacity for marker …

Status and prospects of association mapping in plants

C Zhu, M Gore, ES Buckler, J Yu - The plant genome, 2008 - Wiley Online Library
There is tremendous interest in using association mapping to identify genes responsible for
quantitative variation of complex traits with agricultural and evolutionary importance. Recent …

Lep-MAP3: robust linkage mapping even for low-coverage whole genome sequencing data

P Rastas - Bioinformatics, 2017 - academic.oup.com
Motivation Accurate and dense linkage maps are useful in family-based linkage and
association studies, quantitative trait locus mapping, analysis of genome synteny and other …

Initial sequencing and comparative analysis of the mouse genome

European Bioinformatics Institute: Birney Ewan 3 … - Nature, 2002 - nature.com
The sequence of the mouse genome is a key informational tool for understanding the
contents of the human genome and a key experimental tool for biomedical research. Here …

Biology and medicine in the landscape of quantum advantages

BA Cordier, NPD Sawaya… - Journal of the …, 2022 - royalsocietypublishing.org
Quantum computing holds substantial potential for applications in biology and medicine,
spanning from the simulation of biomolecules to machine learning methods for subtyping …

Genetic design and statistical power of nested association mapping in maize

J Yu, JB Holland, MD McMullen, ES Buckler - Genetics, 2008 - academic.oup.com
We investigated the genetic and statistical properties of the nested association mapping
(NAM) design currently being implemented in maize (26 diverse founders and 5000 distinct …

Rapid and cost-effective polymorphism identification and genotyping using restriction site associated DNA (RAD) markers

MR Miller, JP Dunham, A Amores, WA Cresko… - Genome …, 2007 - genome.cshlp.org
R estriction site a ssociated D NA (RAD) tags are a genome-wide representation of every
site of a particular restriction enzyme by short DNA tags. Most organisms segregate large …

Mammalian circadian biology: elucidating genome-wide levels of temporal organization

PL Lowrey, JS Takahashi - Annu. Rev. Genomics Hum. Genet., 2004 - annualreviews.org
▪ Abstract During the past decade, the molecular mechanisms underlying the mammalian
circadian clock have been defined. A core set of circadian clock genes common to most cells …

Epistasis: too often neglected in complex trait studies?

Ö Carlborg, CS Haley - Nature Reviews Genetics, 2004 - nature.com
Interactions among loci or between genes and environmental factors make a substantial
contribution to variation in complex traits such as disease susceptibility. Nonetheless, many …

Accuracy of genotypic value predictions for marker-based selection in biparental plant populations

RE Lorenzana, R Bernardo - Theoretical and applied genetics, 2009 - Springer
The availability of cheap and abundant molecular markers has led to plant-breeding
methods that rely on the prediction of genotypic value from marker data, but published …