Targeted drug delivery to the colon offers a myriad of benefits, including treatment of local
diseases, direct access to unique therapeutic targets and the potential for increasing …

The incidence of inflammatory bowel disease (IBD) is rapidly rising throughout the world.
Although tremendous efforts have been made, limited therapeutics are available for IBD …

Background Ulcerative colitis is a type of chronic inflammatory bowel disease closely
associated with gut microbiota dysbiosis and intestinal homeostasis dysregulation. Barley …

Abstract Berberine (BBR), a naturally-occurring isoquinoline alkaloid isolated from several
Chinese herbal medicines, has been widely used for the treatment of dysentery and colitis …

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal
tract. Although the etiology and pathogenesis of IBD remain unclear, both genetic …

Abstract Three-dimensional printing (3DP) is a highly disruptive technology with the
potential to change the way pharmaceuticals are designed, prescribed and produced …

The purpose of the current study was to investigate the effect of dietary dihydroquercetin
(DHQ) supplementation on dextran sodium sulfate (DSS)-induced colitis in mice. Mice were …

Mammalian intestine contains a large diversity of commensal microbiota, which is far more
than the number of host cells. Probiotics play an insecure and protective role against the …

Thyme (Thymus vulgaris L.) is an important medicinal and edible homologous plant, and the
composition and bioactivity of its polyphenol extracts have attracted widespread attention …

Intestine is always exposed to external environment and intestinal microorganism; thus it is
more sensitive to dysfunction and dysbiosis, leading to intestinal inflammation, such as …