Cutaneous Malassezia: Commensal, Pathogen, or Protector?

SH Vijaya Chandra, R Srinivas… - Frontiers in cellular …, 2021 - frontiersin.org
The skin microbial community is a multifunctional ecosystem aiding prevention of infections
from transient pathogens, maintenance of host immune homeostasis, and skin health. A …

Seborrheic dermatitis—Looking beyond Malassezia

TC Wikramanayake, LJ Borda… - Experimental …, 2019 - Wiley Online Library
Seborrhoeic Dermatitis (SD) is a very common chronic and/or relapsing inflammatory skin
disorder whose pathophysiology remains poorly understood. Yeast of the genus Malassezia …

Practice parameter for the diagnosis and management of primary immunodeficiency

FA Bonilla, DA Khan, ZK Ballas, J Chinen… - Journal of Allergy and …, 2015 - Elsevier
The American Academy of Allergy, Asthma & Immunology (AAAAI) and the American
College of Allergy, Asthma & Immunology (ACAAI) have jointly accepted responsibility for …

Lethal infectious diseases as inborn errors of immunity: toward a synthesis of the germ and genetic theories

JL Casanova, L Abel - Annual Review of Pathology …, 2021 - annualreviews.org
It was first demonstrated in the late nineteenth century that human deaths from fever were
typically due to infections. As the germ theory gained ground, it replaced the old, unproven …

YAP/TAZ activation as a target for treating metastatic cancer

JSA Warren, Y Xiao, JM Lamar - Cancers, 2018 - mdpi.com
Yes-Associated Protein (YAP) and Transcriptional Co-activator with PDZ-binding Motif (TAZ)
have both emerged as important drivers of cancer progression and metastasis. YAP and …

The Hippo pathway: immunity and cancer

Z Taha, H J. Janse van Rensburg, X Yang - Cancers, 2018 - mdpi.com
Since its discovery, the Hippo pathway has emerged as a central signaling network in
mammalian cells. Canonical signaling through the Hippo pathway core components …

Primary immunodeficiencies underlying fungal infections

F Lanternier, S Cypowyj, C Picard… - Current opinion in …, 2013 - journals.lww.com
CMC, invasive candidiasis, invasive aspergillosis, deep dermatophytosis, pneumocystosis,
and endemic mycoses can all be caused by PIDs. Each type of infection is highly suggestive …

Model systems of human papillomavirus‐associated disease

J Doorbar - The Journal of pathology, 2016 - Wiley Online Library
Human papillomaviruses (HPVs) cause a range of serious diseases, including the vast
majority of cervical cancers, most anal cancers and around half of head and neck cancers …

The human CIB1–EVER1–EVER2 complex governs keratinocyte-intrinsic immunity to β-papillomaviruses

SJ De Jong, A Créquer, I Matos, D Hum… - Journal of Experimental …, 2018 - rupress.org
Patients with epidermodysplasia verruciformis (EV) and biallelic null mutations of TMC6
(encoding EVER1) or TMC8 (EVER2) are selectively prone to disseminated skin lesions due …

Human Beta‐papillomavirus infection and keratinocyte carcinomas

KD Quint, RE Genders, MNC De Koning… - The Journal of …, 2015 - Wiley Online Library
Although the role of oncogenic human Alpha‐papillomaviruses (HPVs) in the development
of mucosal carcinomas at different body sites (eg cervix, anus, oropharynx) is fully …