Pharmacotherapy considerations in patients who develop acute kidney injury during anti-cancer therapy

E Parodi, M Rossi, A Bottiglieri, M Ladetto… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Acute kidney injury (AKI) frequently develops in patients receiving cancer
therapy and requires a wide differential diagnosis due to possible role of unique cancer and …

[HTML][HTML] Constructing training set using distance between learnt graphical models of time series data on patient physiology, to predict disease scores

D Chakrabarty, K Wang, G Roy, A Bhojgaria, C Zhang… - Plos one, 2023 - journals.plos.org
Interventional endeavours in medicine include prediction of a score that parametrises a new
subject's susceptibility to a given disease, at the pre-onset stage. Here, for the first time, we …

Cord Blood Transplantation for Very Early-Onset Inflammatory Bowel Disease Caused by Interleukin-10 Receptor Deficiency

P Wang, X Qian, W Jiang, H Wang, Y Wang… - Journal of Clinical …, 2024 - Springer
Abstract Purpose Interleukin-10 receptor (IL-10R) deficiency can result in life-threatening
very early-onset inflammatory bowel disease (VEO-IBD). Umbilical cord blood …

[HTML][HTML] Optimization of methods for intrasplenic administration of human amniotic epithelial cells in order to perform safe and effective cell-based therapy for liver …

P Czekaj, M Król, E Kolanko, P Wieczorek… - Stem Cell Reviews and …, 2024 - Springer
In animal experimental models the administration of stem cells into the spleen should
ensure high effectiveness of their implantation in the liver due to a direct vascular connection …

Defibrotide prophylaxis for prevention of sinusoidal obstruction syndrome

M Shibusawa, T Tanimoto - The Lancet Haematology, 2023 - thelancet.com
We read with interest the multicentre phase 3 trial by Stephan A Grupp and colleagues1 on
defibrotide plus best standard of care compared with best supportive care for the prevention …

Gemtuzumab Ozogamicin in Acute Myeloid Leukemia: Efficacy, Toxicity, and Resistance Mechanisms—A Systematic Review

A Collados-Ros, M Muro, I Legaz - Biomedicines, 2024 - mdpi.com
Acute myeloid leukemia (AML) is a diverse group of leukemias characterized by the
uncontrolled proliferation of clonal neoplastic hematopoietic precursor cells with …

Functions of the endothelium and its role in hematopoietic cell transplantation

I Kozanoglu, F Pepedil-Tanrikulu - Transfusion and Apheresis Science, 2022 - Elsevier
The endothelium is a single-layered structure that responds to physical and chemical
signals with various factors it synthesizes. In the early days of its discovery, as the inner wall …

[HTML][HTML] Analysis of risk factors for hepatic sinusoidal obstruction syndrome following allogeneic hematopoietic stem cell transplantation in pediatric patients

J Kloehn, G Brodt, J Ernst, B Gruhn - Journal of Cancer Research and …, 2022 - Springer
Purpose Hepatic sinusoidal obstruction syndrome (SOS) represents a serious complication
following hematopoietic stem cell transplantation (HSCT). Our study aimed to investigate …

Impact of defibrotide in the prevention of acute graft-versus-host disease following allogeneic hematopoietic cell transplantation

R Tilmont, I Yakoub-Agha, N Ramdane… - Annals of …, 2022 - journals.sagepub.com
Background Defibrotide is indicated for patients who develop severe sinusoidal obstructive
syndrome following allogeneic hematopoietic cell transplantation (allo-HCT). Preclinical …

Value of contrast-enhanced ultrasound for vascular diseases of the liver–current indications and open questions

I Wiest, ES Zadeh, C Görg, A Teufel… - Zeitschrift für …, 2023 - thieme-connect.com
Contrast-enhanced ultrasonography (CEUS) is a widely available and well-tolerated
technique that can expand the diagnosis of a variety of vascular liver diseases. This paper …