DNA methylation data have become a valuable source of information for biomarker
development, because, unlike static genetic risk estimates, DNA methylation varies …

Single-cell exposomics, a revolutionary approach that investigates cell–environment
interactions at cellular and subcellular levels, stands distinct from conventional bulk …

Importance American Indian communities experience a high burden of coronary heart
disease (CHD). Strategies are needed to identify individuals at risk and implement …

The recent increase in obesity levels across many countries is likely to be driven by
nongenetic factors. The epigenetic modification DNA methylation (DNAm) may help to …

Objective Obesity is a significant public health concern across the globe. Research
investigating epigenetic mechanisms related to obesity and obesity‐associated conditions …

Background Individuals born very low birthweight (VLBW) are at increased risk of impaired
cardiovascular and respiratory function in adulthood. To identify markers to predict future risk …

Epigenetic studies of CVDs have the promise to yield both mechanistic insights as well as
adjunct treatments (repurposed drugs and apabetalone). The overall concept of precision …

We have previously shown that blood global DNA methylation (DNAm) differs between
postprandial state (PS) and fasting state (FS) and is associated with BMI and …

Consistent associations between whole blood DNA methylation (DNAm) levels at several
single genomic (ie CpG) sites and both individual and aggregated cardiometabolic …

Background Maternal body size, nutrition, and hyperglycemia contribute to neonatal body
size and composition. There is little information on maternal-fetal transmission of messages …