[HTML][HTML] Targeting oxidative stress as a therapeutic approach for idiopathic pulmonary fibrosis

C Estornut, J Milara, MA Bayarri, N Belhadj… - Frontiers in …, 2022 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease characterized by an
abnormal reepithelialisation, an excessive tissue remodelling and a progressive fibrosis …

[HTML][HTML] Role of Nrf2 in disease: Novel molecular mechanisms and therapeutic approaches–Pulmonary disease/asthma

C Audousset, T McGovern, JG Martin - Frontiers in Physiology, 2021 - frontiersin.org
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a major transcription factor involved in
redox homeostasis and in the response induced by oxidative injury. Nrf2 is present in an …

ATF3-activated accelerating effect of LINC00941/lncIAPF on fibroblast-to-myofibroblast differentiation by blocking autophagy depending on ELAVL1/HuR in …

J Zhang, H Wang, H Chen, H Li, P Xu, B Liu, Q Zhang… - Autophagy, 2022 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is characterized by lung scarring and has no effective
treatment. Fibroblast-to-myofibroblast differentiation and myofibroblast proliferation and …

[HTML][HTML] ROS-responsive liposomes as an inhaled drug delivery nanoplatform for idiopathic pulmonary fibrosis treatment via Nrf2 signaling

J Liu, Z Wu, Y Liu, Z Zhan, L Yang, C Wang… - Journal of …, 2022 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic disease with
pathophysiological characteristics of transforming growth factor-β (TGF-β), and reactive …

[HTML][HTML] Hippo signaling pathway and respiratory diseases

W Tang, M Li, X Yangzhong, X Zhang, A Zu… - Cell Death …, 2022 - nature.com
The hippo signaling pathway is a highly conserved evolutionary signaling pathway that
plays an important role in regulating cell proliferation, organ size, tissue development, and …

[HTML][HTML] The role of Nrf2 in pulmonary fibrosis: molecular mechanisms and treatment approaches

Y Wang, J Wei, H Deng, L Zheng, H Yang, X Lv - Antioxidants, 2022 - mdpi.com
Pulmonary fibrosis is a chronic, progressive, incurable interstitial lung disease with high
mortality after diagnosis and remains a global public health problem. Despite advances and …

[HTML][HTML] Molecular mechanisms of ferroptosis and its role in prostate cancer therapy

S Wang, W Wei, N Ma, Y Qu, Q Liu - Critical reviews in oncology …, 2022 - Elsevier
Prostate cancer (PCa) is a highly prevalent disease that affects men's health worldwide and
is the second most common malignancy in males. Ferroptosis is a novel form of …

[HTML][HTML] Roles of NRF2 in fibrotic diseases: from mechanisms to therapeutic approaches

W Hao, M Li, Q Cai, S Wu, X Li, Q He, Y Hu - Frontiers in Physiology, 2022 - frontiersin.org
Fibrosis is a persistent inflammatory response that causes scarring and tissue sclerosis by
stimulating myofibroblasts to create significant quantities of extracellular matrix protein …

Anticancer activity of broccoli, its organosulfur and polyphenolic compounds

A Gasmi, A Gasmi Benahmed, M Shanaida… - Critical Reviews in …, 2023 - Taylor & Francis
The use of natural bioactive constituents from various food sources for anticancer purposes
has become increasingly popular worldwide. Broccoli (Brassica oleracea var. italica) is on …

[HTML][HTML] Bufei huoxue capsule alleviates bleomycin-induced pulmonary fibrosis in mice via TGF-β1/Smad2/3 signaling

Y Li, W Qin, Q Liang, J Zeng, Q Yang, Y Chen… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Bufei huoxue (BFHX) is a Traditional Chinese Medicine
formulation that consists of Astragalus Exscapus L, Paeonia Lactiflora Pall, and Psoralea …