Global rural health disparities in Alzheimer's disease and related dementias: State of the science

LAK Wiese, A Gibson, MA Guest… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION Individuals living in rural communities are at heightened risk for
Alzheimer's disease and related dementias (ADRD), which parallels other persistent place …

An examination of the relationship among plasma brain derived neurotropic factor, peripheral vascular function, and body composition with cognition in midlife African …

MK Traylor, AJ Bauman, N Saiyasit… - Frontiers in Aging …, 2022 - frontiersin.org
African American/Black individuals have been excluded from several lines of prominent
neuroscience research, despite exhibiting disproportionately higher risk factors associated …

Biomarkers of Alzheimer's disease in Black and/or African American Alzheimer's Disease Neuroimaging Initiative (ADNI) participants

RC Groechel, Y Tripodis, ML Alosco, J Mez, WQ Qiu… - Neurobiology of …, 2023 - Elsevier
Majority of dementia research is conducted in non-Hispanic White participants despite a
greater prevalence of dementia in other racial groups. To obtain a better understanding of …

Arterial stiffness mediates the association between age and processing speed at low levels of microvascular function in humans across the adult lifespan

KV Ransom, MK Traylor, GB Batman… - American Journal …, 2024 - journals.physiology.org
The function of micro-and macrovessels within the peripheral vasculature has been
identified as a target for the investigation of potential cardiovascular-based promoters of …

Cognitive decline, Aβ pathology, and blood–brain barrier function in aged 5xFAD mice

G Nehra, S Promsan, R Yubolphan… - Fluids and Barriers of …, 2024 - Springer
Abstract Background Patients with Alzheimer's disease (AD) develop blood–brain barrier
dysfunction to varying degrees. How aging impacts Aβ pathology, blood–brain barrier …

Aerobic Exercise, Training Dose, and Cardiorespiratory Fitness: Effects and Relationships with Resting Plasma Neurotrophic Factors in Alzheimer's Dementia

DL Salisbury, D Li, M Todd, TKS Ng, F Yu - Journal of Vascular Diseases, 2023 - mdpi.com
Background: Vascular health is increasingly recognized for its roles in the pathogenesis and
progression of Alzheimer's disease (AD). The objective of this study was to investigate …

Elecsys Cerebrospinal Fluid Immunoassays Accurately Detect Alzheimer's Disease Regardless of Concomitant Small Vessel Disease

M Ortner, K Lanz, O Goldhardt… - Journal of …, 2023 - content.iospress.com
Background: Differentiating dementia due to small vessel disease (SVD) from dementia due
to Alzheimer's disease (AD) with concomitant SVD is challenging in clinical practice …

[PDF][PDF] IL-4 调控小胶质细胞极化在血管性认知障碍中的作用机制研究进展

李倩倩, 李小黎, 陈雨菲, 崔莹雪, 王少松… - 中国实用神经疾病 …, 2022 - cn-shenjing.com
血管性痴呆(vascular dementia, VD) 的核心症状是认知功能障碍. 大脑缺血后小胶质细胞被激活
, 进而诱导神经炎症反应是血管性认知功能障碍发生的关键. 既往部分研究认为 …

Sex and Age Differences in Near-infrared Spectroscopy Responses and the Resulting Influences on Cognition

MK Traylor - 2024 - jagworks.southalabama.edu
Vascular dysfunction is the earliest known marker of neurodegeneration. However, limited
research has been conducted to determine if changes in peripheral vascular function track …