Coacervates are condensed liquid-like droplets, usually formed with oppositely charged
polymeric molecules. They have been studied extensively in colloid and interface science …

Motions in biomolecules are critical for biochemical reactions. In cells, many biochemical
reactions are executed inside of biomolecular condensates formed by ultradynamic …

Many intrinsically disordered proteins (IDPs) may undergo liquid–liquid phase separation
(LLPS) and participate in the formation of membraneless organelles in the cell, thereby …

Liquid phase separation into two or more coexisting phases has emerged as a new
paradigm for understanding subcellular organization, prebiotic life, and the origins of …

Aggregation of the microtubule-associated protein tau plays a major role in Alzheimer's
disease and several other neurodegenerative disorders. An exciting recent development is …

Aberrant aggregation of the misfolded presynaptic protein, α-Synuclein (α-Syn) into Lewy
body (LB) and Lewy neuritis (LN) is a major pathological hallmark of Parkinson's disease …

Growth-associated protein-43 (GAP-43) and brain acid-soluble protein 1 (BASP1) regulate
actin dynamics and presynaptic vesicle cycling at axon terminals, thereby facilitating axonal …

A variety of membraneless organelles, often termed “biological condensates”, play an
important role in the regulation of cellular processes such as gene transcription, translation …

Emerging evidence indicates that liquid–liquid phase separation, the formation of a
condensed molecular assembly within another diluted aqueous solution, is a means for cells …

The concept of liquid–liquid phase separation (LLPS) has emerged as an intriguing
mechanism for the organization of membraneless compartments in cells. The alcohol 1, 6 …