Cancer is among the leading causes of death worldwide and it is estimated that in 2040
more than 29 million people will be diagnosed with some type of cancer. The most prevalent …

Solid tumors have a unique tumor microenvironment (TME), which includes hypoxia, low
acidity, and high hydrogen peroxide and glutathione (GSH) levels, among others. These …

The incidence of adenocarcinoma of the esophagogastric junction (AEG) has been rapidly
increasing in recent decades, but its molecular alterations and subtypes are still obscure …

Background Artificial intelligence (AI) is capable of integrating a large amount of related
information to predict therapeutic relationships such as disease treatment with known drugs …

Non-small cell lung cancer (NSCLC) is ranked first worldwide amongst deadly cancers with
poor patient survival rate. While chemotherapy, radiation and surgery are available …

Simple Summary Synthetic lethality approaches to cancer therapy involves combining
events to cause cancer cell death. Using this strategy, major advances have occurred in the …

The development of protein kinase inhibitors (PKIs) has gained significance owing to their
therapeutic potential for diseases like cancer. In addition, there has been a rise in refining …

Building upon our previous investigation of genomic, epigenomic, and transcriptomic
profiles of prostate cancer in China, we conducted a comprehensive analysis of proteomic …

Deviant expressions of the tyrosine kinase AXL receptor are strongly correlated with a
plethora of malignancies. Henceforth, the topic of targeting AXL is beginning to gain …

The global burden of cancer necessitates rapid and ongoing development of effective
cancer therapies. One promising approach in this context is the repurposing of existing non …