Factors contributing to medication adherence in patients with a chronic condition: a scoping review of qualitative research

K Kvarnström, A Westerholm, M Airaksinen, H Liira - Pharmaceutics, 2021 - mdpi.com
Introduction: Medication adherence continues to be a significant challenge in healthcare,
and there is a shortage of effective interventions in this area. This scoping review studied the …

Gastrointestinal side effects associated with antidepressant treatments in patients with major depressive disorder: a systematic review and meta-analysis

V Oliva, M Lippi, R Paci, L Del Fabro… - Progress in Neuro …, 2021 - Elsevier
Gastrointestinal side effects (SEs) are frequently observed in patients with major depressive
disorder (MDD) while taking antidepressants and may lead to treatment discontinuation. The …

Cannabidiol induces rapid and sustained antidepressant-like effects through increased BDNF signaling and synaptogenesis in the prefrontal cortex

AJ Sales, MV Fogaça, AG Sartim, VS Pereira… - Molecular …, 2019 - Springer
Currently available antidepressants have a substantial time lag to induce therapeutic
response and a relatively low efficacy. The development of drugs that addresses these …

Factors influencing medication adherence among patients with severe mental disorders from the perspective of mental health professionals

M Deng, S Zhai, X Ouyang, Z Liu, B Ross - BMC psychiatry, 2022 - Springer
Background Medication adherence is a common issue influenced by various factors among
patients with severe mental disorders worldwide. However, most literature to date has been …

Psilocybin for treatment-resistant depression without psychedelic effects: study protocol for a 4-week, double-blind, proof-of-concept randomised controlled trial

MI Husain, DM Blumberger, DJ Castle, N Ledwos… - BJPsych …, 2023 - cambridge.org
BackgroundRandomised controlled trials (RCTs) of psilocybin have reported large
antidepressant effects in adults with major depressive disorder and treatment-resistant …

How to improve adherence to antidepressant treatments in patients with major depression: a psychoeducational consensus checklist

B Dell'Osso, U Albert, G Carrà, M Pompili… - Annals of General …, 2020 - Springer
Studies conducted in primary care as well as in psychiatric settings show that more than half
of patients suffering from major depressive disorder (MDD) have poor adherence to …

Mental health literacy: A systematic review of knowledge and beliefs about mental disorders in Malaysia

K Munawar, F Mukhtar, FR Choudhry… - Asia‐Pacific …, 2022 - Wiley Online Library
Background Mental health problems in Malaysia are on a rise. This study aimed at
performing a systematic review of mental health literacy (MHL) in Malaysia. Methods …

Association between childhood trauma and medication adherence among patients with major depressive disorder: the moderating role of resilience

H Wang, Y Liao, L Guo, H Zhang, Y Zhang, W Lai… - BMC psychiatry, 2022 - Springer
Background Suboptimal medication adherence is a major reason for failure in the
management of major depressive disorder (MDD), childhood trauma might be an essential …

Efficacy, tolerability, and safety of toludesvenlafaxine for the treatment of major depressive disorder—A narrative review

O Vasiliu - Pharmaceuticals, 2023 - mdpi.com
The estimated rate of treatment-resistant major depressive disorder (TRD) remains higher
than 30%, even after the discovery of multiple classes of antidepressants in the last 7 …

Effect of adjunctive simvastatin on depressive symptoms among adults with treatment-resistant depression: a randomized clinical trial

MI Husain, IB Chaudhry, AB Khoso, T Kiran… - JAMA Network …, 2023 - jamanetwork.com
Importance Immune-metabolic disturbances have been implicated in the pathophysiology of
major depressive disorder and may be more prominent in individuals with treatment …